Techniques for mechanical stimulation of cells in vitro: a review

被引:391
作者
Brown, TD [1 ]
机构
[1] Univ Iowa, Dept Orthopaed Surg, Orthopaed Biomech Lab, Iowa City, IA 52242 USA
关键词
D O I
10.1016/S0021-9290(99)00177-3
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
A wide variety of laboratory apparatuses have been devised for mechanical stimulation of cell and tissue cultures. This article reviews the functional attributes of several dozen systems developed for that purpose, including their major advantages and disadvantages. These devices can be categorized in terms of their primary loading modality: compression (hydrostatic pressure or direct platen contact), longitudinal stretch, bending, axisymmetric substrate bulge, in-plane substrate distention, fluid shear stress, or combined substrate distention and fluid sheer. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
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页码:3 / 14
页数:12
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