Polycythemia vera in a child following treatment for acute lymphoblastic leukemia

被引：5

作者：

Sutherland, ND

Gonzalez-Peralta, R

Douglas-Nikitin, V

Hunger, SP

机构：

[1] Univ Florida, Coll Med, Dept Pediat, Gainesville, FL 32610 USA

[2] Univ Florida, Coll Med, Dept Pathol, Gainesville, FL 32610 USA

[3] Univ Florida, Coll Med, Shands Canc Ctr, Gainesville, FL 32610 USA

来源：

JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2004年 / 26卷 / 05期

关键词：

polycythemia vera; acute lymphoblastic leukemia; Budd-Chiari syndrome; atrioventricular canal;

D O I：

10.1097/00043426-200405000-00012

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Polycythemia vera (PV), a hematologic stem cell disorder characterized by predominant erythroid proliferation, is extremely rare in childhood. Some PV patients develop acute leukemia, especially acute myelogenous leukemia, but cases of PV occurring after treatment of acute leukemia are rare. The authors describe a girl with an atrioventricular canal who was diagnosed with acute lymphoblastic leukemia (ALL) at 23 months of age, was cured with chemotherapy, and developed PV 7 years later. She went on to develop hepatic complications of PV that culminated in death from liver disease at 20 years of age, without recurrence of ALL.

引用

页码：315 / 319

页数：5