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Clinical Predictors of Ketamine Response in Treatment-Resistant Major Depression
被引:119
作者:

Niciu, Mark J.
论文数: 0 引用数: 0
h-index: 0
机构:
NIMH, Expt Therapeut & Pathophysiol Branch, IRP, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, IRP, NIH, Bethesda, MD 20892 USA

Luckenbaugh, David A.
论文数: 0 引用数: 0
h-index: 0
机构:
NIMH, Expt Therapeut & Pathophysiol Branch, IRP, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, IRP, NIH, Bethesda, MD 20892 USA

Ionescu, Dawn F.
论文数: 0 引用数: 0
h-index: 0
机构:
NIMH, Expt Therapeut & Pathophysiol Branch, IRP, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, IRP, NIH, Bethesda, MD 20892 USA

Guevara, Sara
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h-index: 0
机构:
NIMH, Expt Therapeut & Pathophysiol Branch, IRP, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, IRP, NIH, Bethesda, MD 20892 USA

Machado-Vieira, Rodrigo
论文数: 0 引用数: 0
h-index: 0
机构:
NIMH, Expt Therapeut & Pathophysiol Branch, IRP, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, IRP, NIH, Bethesda, MD 20892 USA

Richards, Erica M.
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h-index: 0
机构:
NIMH, Expt Therapeut & Pathophysiol Branch, IRP, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, IRP, NIH, Bethesda, MD 20892 USA

Brutsche, Nancy E.
论文数: 0 引用数: 0
h-index: 0
机构:
NIMH, Expt Therapeut & Pathophysiol Branch, IRP, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, IRP, NIH, Bethesda, MD 20892 USA

Nolan, Neal M.
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h-index: 0
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NIMH, Expt Therapeut & Pathophysiol Branch, IRP, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, IRP, NIH, Bethesda, MD 20892 USA

Zarate, Carlos A., Jr.
论文数: 0 引用数: 0
h-index: 0
机构:
NIMH, Expt Therapeut & Pathophysiol Branch, IRP, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, IRP, NIH, Bethesda, MD 20892 USA
机构:
[1] NIMH, Expt Therapeut & Pathophysiol Branch, IRP, NIH, Bethesda, MD 20892 USA
关键词:
RAPID ANTIDEPRESSANT RESPONSE;
D-ASPARTATE ANTAGONIST;
ADD-ON TRIAL;
BIPOLAR DEPRESSION;
ALCOHOL DEPENDENCE;
MOOD DISORDERS;
GLUTAMATERGIC NEUROTRANSMISSION;
NMDA ANTAGONIST;
FAMILY-HISTORY;
EFFICACY;
D O I:
10.4088/JCP.13m08698
中图分类号:
B849 [应用心理学];
学科分类号:
040203 ;
摘要:
Objective: The N-methyl-d-aspartate receptor antagonist ketamine has rapid antidepressant effects in treatment-resistant major depressive disorder (MDD) and bipolar depression. Clinical predictors may identify those more likely to benefit from ketamine within clinically heterogeneous populations. Method: Data were analyzed from 4 studies of treatment-resistant inpatients with DSM-IV-TR-diagnosed MDD or bipolar I or II depression. Patients who were currently experiencing a moderate-to-severe major depressive episode were enrolled between November 2004 and March 2013. All subjects received a single subanesthetic (0.5 mg/kg) ketamine infusion over 40 minutes. Patients were analyzed at the 230-minute postinfusion time point (n = 108), at day 1 (n = 82), and at day 7 (n = 71). Univariate Pearson correlations were performed for each variable with percent change from baseline in the 17-item Hamilton Depression Rating Scale (HDRS). Multivariate linear regression was then conducted for statistically significant predictors (P =.05, 2-tailed). Results: Higher body mass index correlated with greater HDRS improvement at 230 minutes (standardized beta = -0.30, P =.004) and at day 1 (standardized beta = -0.37, P =.001), but not at day 7 (standardized beta = -0.18, P =.10). Family history of an alcohol use disorder in a first-degree relative was associated with greater HDRS improvement at day 1 (standardized beta = -0.27, P =.014) and day 7 (standardized beta = -0.41, P <.001). No prior history of suicide attempt(s) was associated with greater improvement only at day 7 (standardized beta = 0.28, P =.01). The overall statistical model explained 13%, 23%, and 36% of HDRS percent change variance at 230 minutes, day 1, and day 7, respectively. Conclusions: Despite its post hoc nature, this study identified several clinical correlates of ketamine's rapid and durable antidepressant effects. Further investigation of these relationships is critical for individualized treatment of depression. (C) Copyright 2014 Physicians Postgraduate Press, Inc.
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页码:E417 / E423
页数:7
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- [1] Neural Correlates of Rapid Antidepressant Response to Ketamine in Treatment-Resistant Unipolar Depression: A Preliminary Positron Emission Tomography Study[J]. BIOLOGICAL PSYCHIATRY, 2013, 73 (12) : 1213 - 1221Carlson, Paul J.论文数: 0 引用数: 0 h-index: 0机构: Univ Utah, Sch Med, Salt Lake City Vet Affairs Med, Salt Lake City, UT USA Univ Utah, Sch Med, Dept Psychiat, Salt Lake City, UT USA Univ Utah, Sch Med, Salt Lake City Vet Affairs Med, Salt Lake City, UT USA论文数: 引用数: h-index:机构:Nugent, Allison C.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD USA Univ Utah, Sch Med, Salt Lake City Vet Affairs Med, Salt Lake City, UT USAIbrahim, Lobna论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD USA Univ Utah, Sch Med, Salt Lake City Vet Affairs Med, Salt Lake City, UT USALuckenbaugh, David A.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD USA Univ Utah, Sch Med, Salt Lake City Vet Affairs Med, Salt Lake City, UT USABrutsche, Nancy论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD USA Univ Utah, Sch Med, Salt Lake City Vet Affairs Med, Salt Lake City, UT USAHerscovitch, Peter论文数: 0 引用数: 0 h-index: 0机构: NIH, Ctr Clin, Positron Emiss Tomog Dept, Bethesda, MD 20892 USA Univ Utah, Sch Med, Salt Lake City Vet Affairs Med, Salt Lake City, UT USAManji, Husseini K.论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev, Titusville, NJ USA Univ Utah, Sch Med, Salt Lake City Vet Affairs Med, Salt Lake City, UT USAZarate, Carlos A., Jr.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD USA Univ Utah, Sch Med, Salt Lake City Vet Affairs Med, Salt Lake City, UT USADrevets, Wayne C.论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev, Titusville, NJ USA Laureate Inst Brain Res, Dept Psychiat, Tulsa, OK USA Univ Utah, Sch Med, Salt Lake City Vet Affairs Med, Salt Lake City, UT USA
- [2] Synaptic Potentiation Is Critical for Rapid Antidepressant Response to Ketamine in Treatment-Resistant Major Depression[J]. BIOLOGICAL PSYCHIATRY, 2012, 72 (07) : 555 - 561Cornwell, Brian R.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Sect Neurobiol Fear & Anxiety, NIH, Bethesda, MD 20892 USA NIMH, Sect Neurobiol Fear & Anxiety, NIH, Bethesda, MD 20892 USASalvadore, Giacomo论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USA Johnson & Johnson, Pharmaceut Res & Dev, Titusville, NJ USA NIMH, Sect Neurobiol Fear & Anxiety, NIH, Bethesda, MD 20892 USAFurey, Maura论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USA NIMH, Sect Neurobiol Fear & Anxiety, NIH, Bethesda, MD 20892 USAMarquardt, Craig A.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USA NIMH, Sect Neurobiol Fear & Anxiety, NIH, Bethesda, MD 20892 USABrutsche, Nancy E.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USA NIMH, Sect Neurobiol Fear & Anxiety, NIH, Bethesda, MD 20892 USAGrillon, Christian论文数: 0 引用数: 0 h-index: 0机构: NIMH, Sect Neurobiol Fear & Anxiety, NIH, Bethesda, MD 20892 USA NIMH, Sect Neurobiol Fear & Anxiety, NIH, Bethesda, MD 20892 USAZarate, Carlos A., Jr.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USA NIMH, Sect Neurobiol Fear & Anxiety, NIH, Bethesda, MD 20892 USA
- [3] A Randomized Add-on Trial of an N-methyl-D-aspartate Antagonist in Treatment-Resistant Bipolar Depression[J]. ARCHIVES OF GENERAL PSYCHIATRY, 2010, 67 (08) : 793 - 802Diazgranados, Nancy论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USA NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USAIbrahim, Lobna论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USA NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USABrutsche, Nancy E.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USA NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USANewberg, Andrew论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USA NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USAKronstein, Phillip论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USA NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USAKhalife, Sami论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USA NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USAKammerer, William A.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USA NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USAQuezado, Zenaide论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USA NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USALuckenbaugh, David A.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USA NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USASalvadore, Giacomo论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USA NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USAMachado-Vieira, Rodrigo论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USA NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USAManji, Husseini K.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USA NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USAZarate, Carlos A., Jr.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USA NIMH, Expt Therapeut Mood & Anxiety Disorders Program, NIH, Dept Hlth & Human Serv,Clin Res Ctr, Bethesda, MD 20892 USA
- [4] Signaling pathways underlying the rapid antidepressant actions of ketamine[J]. NEUROPHARMACOLOGY, 2012, 62 (01) : 35 - 41Duman, Ronald S.论文数: 0 引用数: 0 h-index: 0机构: Yale Univ, Sch Med, Dept Psychiat, New Haven, CT 06508 USA Yale Univ, Sch Med, Dept Psychiat, New Haven, CT 06508 USALi, Nanxin论文数: 0 引用数: 0 h-index: 0机构: Yale Univ, Sch Med, Dept Psychiat, New Haven, CT 06508 USALiu, Rong-Jian论文数: 0 引用数: 0 h-index: 0机构: Yale Univ, Sch Med, Dept Psychiat, New Haven, CT 06508 USADuric, Vanja论文数: 0 引用数: 0 h-index: 0机构: Yale Univ, Sch Med, Dept Psychiat, New Haven, CT 06508 USAAghajanian, George论文数: 0 引用数: 0 h-index: 0机构: Yale Univ, Sch Med, Dept Psychiat, New Haven, CT 06508 USA
- [5] Concomitant BDNF and sleep slow wave changes indicate ketamine-induced plasticity in major depressive disorder[J]. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2013, 16 (02) : 301 - 311Duncan, Wallace C., Jr.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USASarasso, Simone论文数: 0 引用数: 0 h-index: 0机构: Univ Wisconsin, Dept Psychiat, Madison, WI 53706 USA NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USAFerrarelli, Fabio论文数: 0 引用数: 0 h-index: 0机构: Univ Wisconsin, Dept Psychiat, Madison, WI 53706 USA NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USASelter, Jessica论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USARiedner, Brady A.论文数: 0 引用数: 0 h-index: 0机构: Univ Wisconsin, Dept Psychiat, Madison, WI 53706 USA NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USAHejazi, Nadia S.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USAYuan, Peixiong论文数: 0 引用数: 0 h-index: 0机构: NIMH, Clin Brain Disorders Branch, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USABrutsche, Nancy论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USAManji, Husseini K.论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev, Titusville, NJ USA NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USATononi, Giulio论文数: 0 引用数: 0 h-index: 0机构: Univ Wisconsin, Dept Psychiat, Madison, WI 53706 USA NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USAZarate, Carlos A., Jr.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USA
- [6] Baseline delta sleep ratio predicts acute ketamine mood response in major depressive disorder[J]. JOURNAL OF AFFECTIVE DISORDERS, 2013, 145 (01) : 115 - 119Duncan, Wallace C., Jr.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USASelter, Jessica论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USABrutsche, Nancy论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USASarasso, Simone论文数: 0 引用数: 0 h-index: 0机构: Univ Wisconsin, Dept Psychiat, Madison, WI 53719 USA Univ Milan, Dept Biomed & Clin Sci Luigi Sacco, Milan, Italy NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USAZarate, Carlos A., Jr.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USA
- [7] Antidepressant efficacy of the antimuscarinic drug scopolamine - A randomized, placebo-controlled clinical trial[J]. ARCHIVES OF GENERAL PSYCHIATRY, 2006, 63 (10) : 1121 - 1129Furey, Maura L.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Mood & Anxiety Disorders Program, NIH, Bethesda, MD 20892 USA NIMH, Mood & Anxiety Disorders Program, NIH, Bethesda, MD 20892 USADrevets, Wayne C.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Mood & Anxiety Disorders Program, NIH, Bethesda, MD 20892 USA NIMH, Mood & Anxiety Disorders Program, NIH, Bethesda, MD 20892 USA
- [8] Potential of Pretreatment Neural Activity in the Visual Cortex During Emotional Processing to Predict Treatment Response to Scopolamine in Major Depressive Disorder[J]. JAMA PSYCHIATRY, 2013, 70 (03) : 280 - 290Furey, Maura L.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USADrevets, Wayne C.论文数: 0 引用数: 0 h-index: 0机构: Univ Oklahoma, Laureate Inst Brain Res, Coll Med, Tulsa, OK USA Univ Oklahoma, Dept Psychiat, Coll Med, Tulsa, OK USA NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USAHoffman, Elana M.论文数: 0 引用数: 0 h-index: 0机构: Univ Maryland, Dept Psychol, College Pk, MD 20742 USA NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USAFrankel, Erica论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USASpeer, Andrew M.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Lab Brain & Cognit, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USAZarate, Carlos A., Jr.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USA
- [9] Baseline mood-state measures as predictors of antidepressant response to scopolamine[J]. PSYCHIATRY RESEARCH, 2012, 196 (01) : 62 - 67Furey, Maura L.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USANugent, Allison C.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USASpeer, Andrew M.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Lab Brain & Cognit, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USALuckenbaugh, David A.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USAHoffman, Elana M.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USAFrankel, Erica论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USADrevets, Wayne C.论文数: 0 引用数: 0 h-index: 0机构: Laureate Inst Brain Res, Tulsa, OK 74136 USA Univ Oklahoma, Coll Med, Dept Psychiat, Tulsa, OK 74136 USA NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USAZarate, Carlos A., Jr.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, NIH, Bethesda, MD 20892 USA
- [10] Course of Improvement in Depressive Symptoms to a Single Intravenous Infusion of Ketamine vs Add-on Riluzole: Results from a 4-Week, Double-Blind, Placebo-Controlled Study[J]. NEUROPSYCHOPHARMACOLOGY, 2012, 37 (06) : 1526 - 1533Ibrahim, Lobna论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, Div Intramural Res Programs, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, Div Intramural Res Programs, NIH, Bethesda, MD 20892 USA论文数: 引用数: h-index:机构:Franco-Chaves, Jose论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, Div Intramural Res Programs, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, Div Intramural Res Programs, NIH, Bethesda, MD 20892 USABrutsche, Nancy论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, Div Intramural Res Programs, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, Div Intramural Res Programs, NIH, Bethesda, MD 20892 USAHenter, Ioline D.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Mol Imaging Branch, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, Div Intramural Res Programs, NIH, Bethesda, MD 20892 USAKronstein, Phillip论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, Div Intramural Res Programs, NIH, Bethesda, MD 20892 USA US FDA, Silver Spring, MD USA NIMH, Expt Therapeut & Pathophysiol Branch, Div Intramural Res Programs, NIH, Bethesda, MD 20892 USAMoaddel, Ruin论文数: 0 引用数: 0 h-index: 0机构: NIA, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, Div Intramural Res Programs, NIH, Bethesda, MD 20892 USAWainer, Irving论文数: 0 引用数: 0 h-index: 0机构: NIA, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, Div Intramural Res Programs, NIH, Bethesda, MD 20892 USALuckenbaugh, David A.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, Div Intramural Res Programs, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, Div Intramural Res Programs, NIH, Bethesda, MD 20892 USAManji, Husseini K.论文数: 0 引用数: 0 h-index: 0机构: Johnson & Johnson Pharmaceut Res & Dev, Titusville, NJ USA NIMH, Expt Therapeut & Pathophysiol Branch, Div Intramural Res Programs, NIH, Bethesda, MD 20892 USAZarate, Carlos A., Jr.论文数: 0 引用数: 0 h-index: 0机构: NIMH, Expt Therapeut & Pathophysiol Branch, Div Intramural Res Programs, NIH, Bethesda, MD 20892 USA NIMH, Expt Therapeut & Pathophysiol Branch, Div Intramural Res Programs, NIH, Bethesda, MD 20892 USA