RNase III: Genetics and Function; Structure and Mechanism

被引：131

作者：

Court, Donald L. ^{[1
]}

Gan, Jianhua ^{[1
]}

Liang, Yu-He ^{[1
]}

Shaw, Gary X. ^{[1
]}

Tropea, Joseph E. ^{[1
]}

Costantino, Nina ^{[1
]}

Waugh, David S. ^{[1
]}

Ji, Xinhua ^{[1
]}

机构：

[1] NCI, Ctr Canc Res, Frederick, MD 21702 USA

来源：

ANNUAL REVIEW OF GENETICS, VOL 47 | 2013年 / 47卷

关键词：

global gene regulation; dsRNA binding; dsRNA processing; bacteriophage; CRISPR; Dicer; COLI RIBONUCLEASE-III; 16S RIBOSOMAL-RNA; ESCHERICHIA-COLI; MESSENGER-RNA; BACTERIOPHAGE-LAMBDA; STRANDED-RNA; INT GENE; ANTISENSE RNA; HUMAN DICER; ERA GTPASE;

D O I：

10.1146/annurev-genet-110711-155618

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

RNase III is a global regulator of gene expression in Escherichia coli that is instrumental in the maturation of ribosomal and other structural RNAs. We examine here how RNase III itself is regulated in response to growth and other environmental changes encountered by the cell and how, by binding or processing double-stranded RNA (dsRNA) intermediates, RNase III controls the expression of genes. Recent insight into the mechanism of dsRNA binding and processing, gained from structural studies of RNase III, is reviewed. Structural studies also reveal new cleavage sites in the enzyme that can generate longer 3' overhangs.

引用

收藏

页码：405 / +

页数：35

相关论文

共 133 条

[21] Alternative 3'-end processing of U5 snRNA by RNase III [J].

Chanfreau, G ;

AbouElela, S ;

Ares, M ;

Guthrie, C .

GENES & DEVELOPMENT, 1997, 11 (20) :2741-2751

[22] Yeast RNase III as a key processing enzyme in small nucleolar RNAs metabolism [J].

Chanfreau, G ;

Legrain, P ;

Jacquier, A .

JOURNAL OF MOLECULAR BIOLOGY, 1998, 284 (04) :975-988

[23] Crystal structure of ERA: A GTPase-dependent cell cycle regulator containing an RNA binding motif [J].

Chen, X ;

Court, DL ;

Ji, XH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (15) :8396-8401

[24]

Court D.L., 1993, CONTROL MESSENGER RN, P71, DOI DOI 10.1016/B978-0-08-091652-1.50009-8

[25] A new look at bacteriophage λ genetic networks [J].

Court, Donald L. ;

Oppertheim, Amos B. ;

Adhya, Sankar L. .

JOURNAL OF BACTERIOLOGY, 2007, 189 (02) :298-304

[26] An antisense RNA inhibits translation by competing with standby ribosomes [J].

Darfeuille, Fabien ;

Unoson, Cecilia ;

Vogel, Joerg ;

Wagner, E. Gerhart H. .

MOLECULAR CELL, 2007, 26 (03) :381-392

[27] Genetic uncoupling of the dsRNA-binding and RNA cleavage activities of the Escherichia coli endoribonuclease RNase III -: the effect of dsRNA binding on gene expression [J].

Dasgupta, S ;

Fernandez, L ;

Kameyama, L ;

Inada, T ;

Nakamura, Y ;

Pappas, A ;

Court, DL .

MOLECULAR MICROBIOLOGY, 1998, 28 (03) :629-640

[28]

DeLano W.L., 2002, The PyMOL molecular graphics system

[29] CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III [J].

Deltcheva, Elitza ;

Chylinski, Krzysztof ;

Sharma, Cynthia M. ;

Gonzales, Karine ;

Chao, Yanjie ;

Pirzada, Zaid A. ;

Eckert, Maria R. ;

Vogel, Joerg ;

Charpentier, Emmanuelle .

NATURE, 2011, 471 (7340) :602-+

[30] Maturation and Degradation of Ribosomal RNA in Bacteria [J].

Deutscher, Murray P. .

MOLECULAR BIOLOGY OF RNA PROCESSING AND DECAY IN PROKARYOTES, 2009, 85 :369-391

← 1 2 3 4 5 6 7 8 9 10 →