Microfluidic electrospinning of biphasic nanofibers with Janus morphology

被引：41

作者：

Srivastava, Yasmin ^{[1
]}

Marquez, Manuel ^{[2
,3
]}

Thorsen, Todd ^{[1
]}

机构：

[1] MIT, Dept Mech Engn, Cambridge, MA 02139 USA

[2] NIST Ctr Theoret & Computat Nanosci, Gaithersburg, MD 20899 USA

[3] Arizona State Univ, Harrington Dept Bioengn, Tempe, AZ 85287 USA

来源：

BIOMICROFLUIDICS | 2009年 / 3卷 / 01期

关键词：

cellular biophysics; microfluidics; nanostructured materials; polymer fibres; scanning electron microscopy; tissue engineering; transmission electron microscopy; MULTIPLE JETS; FABRICATION; PARTICLES; HOLLOW; DESIGN; CO; MICROPARTICLES; NANOPARTICLES; POLYPYRROLE; ANISOTROPY;

D O I：

10.1063/1.3009288

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

In this paper a method of electrospinning conducting and nonconducting biphasic Janus nanofibers using microfluidic polydimethylsiloxane (PDMS)-based manifolds is described. Key benefits of using microfluidic devices for nanofiber synthesis include rapid prototyping, ease of fabrication, and the ability to spin multiple Janus fibers in parallel through arrays of individual microchannels. Biphasic Janus nanofibers of polyvinylpyrrolidone (PVP)+polypyrrole (PPy)/PVP nanofibers with an average diameter of 250 nm were successfully fabricated using elastomeric microfluidic devices. Fiber characterization and confirmation of the Janus morphology was subsequently carried out using a combination of scanning electron microscopy, energy dispersion spectroscopy, and transmission electron microscopy.

引用

页数：6

共 31 条

[11] Direct fabrication of composite and ceramic hollow nanofibers by electrospinning [J].