Nutritional Therapy in Pediatric Crohn Disease: The Specific Carbohydrate Diet

被引:105
|
作者
Suskind, David L.
Wahbeh, Ghassan
Gregory, Nila
Vendettuoli, Heather
Christie, Dennis
机构
[1] Seattle Childrens Hosp, Dept Pediat, Seattle, WA 98105 USA
[2] Univ Washington, Seattle, WA 98195 USA
关键词
Crohn disease; dietary therapy; low complex carbohydrate; nutritional therapy; pediatrics; specific carbohydrate diet; INFLAMMATORY-BOWEL-DISEASE; ENTERAL NUTRITION; ACTIVITY INDEX; CHILDREN; CORTICOSTEROIDS; MICROBIOTA;
D O I
10.1097/MPG.0000000000000103
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Objectives:Crohn disease is characterized by chronic intestinal inflammation in the absence of a recognized etiology. Nutritional therapy in the form of exclusive enteral nutrition (EEN) has an established role within pediatric Crohn disease. Following exclusive enteral nutrition's success, many dietary therapies focusing on the elimination of specific complex carbohydrates have been anecdotally reported to be successful.Methods:Many of these therapies have not been evaluated scientifically; therefore, we reviewed the medical records of our patients with Crohn disease on the specific carbohydrate diet (SCD).Results:Seven children with Crohn disease receiving the SCD and no immunosuppressive medications were retrospectively evaluated. Duration of the dietary therapy ranged from 5 to 30 months, with an average of 14.610.8 months. Although the exact time of symptom resolution could not be determined through chart review, all symptoms were notably resolved at a routine clinic visit 3 months after initiating the diet. Each patient's laboratory indices, including serum albumin, C-reactive protein, hematocrit, and stool calprotectin, either normalized or significantly, improved during follow-up clinic visits.Conclusions:This chart review suggests that the SCD and other low complex carbohydrate diets may be possible therapeutic options for pediatric Crohn disease. Further prospective studies are required to fully assess the safety and efficacy of the SCD, or any other low complex SCDs in pediatric patients with Crohn disease.
引用
收藏
页码:87 / 91
页数:5
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