Melanoma vaccines

被引：13
作者：
Perales, MA
Wolchok, JD
机构：
[1] Cornell Univ, Mem Sloan Kettering Canc Ctr, Dept Med, Clin Immunol Serv, New York, NY 10021 USA
[2] Cornell Univ, Joan & Sanford I Weill Med Coll, New York, NY 10021 USA
来源：
CANCER INVESTIGATION | 2002年 / 20卷 / 7-8期
关键词：
tumor; vaccine; melanoma; clinical trials;
D O I：
10.1081/CNV-120005918
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The identification of antigens on tumor cells has led to significant contributions to the field of immunotherapy. One of the most active areas under investigation in cancer immunotherapy is the development of vaccines against melanoma antigens. Induction of immunity against tumor antigens can follow multiple routes using different mechanisms. Crucial to the development of active immunization and other immunotherapies is the discovery and understanding of the molecular identity of antigens and the mechanisms involved in tumor immunity as well as escape from immunity. In this review, we will discuss strategies to induce active immunity against melanoma.
引用
收藏
页码：1012 / 1026
页数：15
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