A New Borrelia Species Defined by Multilocus Sequence Analysis of Housekeeping Genes

被引:225
作者
Margos, Gabriele [1 ]
Vollmer, Stephanie A. [1 ]
Cornet, Muriel [2 ]
Garnier, Martine [2 ]
Fingerle, Volker [3 ]
Wilske, Bettina [4 ]
Bormane, Antra [5 ]
Vitorino, Liliana [6 ]
Collares-Pereira, Margarida [6 ]
Drancourt, Michel [7 ]
Kurtenbach, Klaus [1 ]
机构
[1] Univ Bath, Dept Biol & Biochem, Bath BA2 7AY, Avon, England
[2] Inst Pasteur, Ctr Natl Reference Borrelia, F-75724 Paris 15, France
[3] Branch Oberschleissheim, Bayer Landesamt Gesundheit & Lebensmittelsicherhe, Natl Reference Ctr Borrelia, D-85764 Oberschleissheim, Germany
[4] Univ Munich, Max Von Pettenkofer Inst, Natl Reference Ctr Borreliae, D-80336 Munich, Germany
[5] State Agcy Publ Hlth Agcy, LV-1012 Riga, Latvia
[6] Univ Nova Lisboa, Inst Higiene & Med Trop, Unidade Leptospirose & Borreliose Lyme, P-1349008 Lisbon, Portugal
[7] Univ Mediterrane, Fac Med, Unite Rech Malad Infect & Trop Emergentes, CNRS,IRD,UMR 6236,IFR48, Marseille, France
基金
英国惠康基金;
关键词
BURGDORFERI SENSU-LATO; FRAGMENT-LENGTH-POLYMORPHISM; GARINII OSPA SEROTYPE-4; SPIELMANII SP-NOV; JAPONICA SP-NOV; LYME-DISEASE; IXODES-RICINUS; NORTH-AMERICA; RIBOSOMAL-RNA; STRAINS;
D O I
10.1128/AEM.00116-09
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Analysis of Lyme borreliosis (LB) spirochetes, using a novel multilocus sequence analysis scheme, revealed that OspA serotype 4 strains (a rodent-associated ecotype) of Borrelia garinii were sufficiently genetically distinct from bird-associated B. garinii strains to deserve species status. We suggest that OspA serotype 4 strains be raised to species status and named Borrelia bavariensis sp. nov. The rooted phylogenetic trees provide novel insights into the evolutionary history of LB spirochetes.
引用
收藏
页码:5410 / 5416
页数:7
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