The Born in Guangzhou Cohort Study (BIGCS)

被引:71
作者
Qiu, Xiu [1 ]
Lu, Jin-Hua [1 ]
He, Jian-Rong [1 ]
Lam, Kin-bong Hubert [2 ]
Shen, Song-Ying [1 ]
Guo, Yong [1 ]
Kuang, Ya-Shu [1 ]
Yuan, Ming-Yang [1 ]
Qiu, Lan [1 ]
Chen, Nian-Nian [1 ]
Lu, Min-Shan [1 ]
Li, Wei-Dong [1 ]
Xing, Yan-Fei [1 ]
Zhou, Feng-Juan [1 ]
Bartington, Suzanne [3 ]
Cheng, Kar Keung [3 ]
Xia, Hui-Min [1 ]
机构
[1] Guangzhou Med Univ, Div Birth Cohort Study, Guangzhou Women & Childrens Med Ctr, 9 Junsui Rd, Guangzhou 510623, Guangdong, Peoples R China
[2] Univ Oxford, Nuffield Dept Populat Hlth, Oxford, England
[3] Univ Birmingham, Inst Appl Hlth Res, Birmingham, W Midlands, England
基金
中国国家自然科学基金;
关键词
Design; Cohort study; Child; Pregnancy; Record linkage; HYPERGLYCEMIA; DEPRESSION; PREGNANCY; DIETARY;
D O I
10.1007/s10654-017-0239-x
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
The Born in Guangzhou Cohort Study (BIGCS) is a large-scale prospective observational study investigating the role of social, biological and environmental influences on pregnancy and child health and development in an urban setting in southern China. Pregnant women who reside in Guangzhou and who attend Guangzhou Women and Children's Medical Center (GWCMC) for antenatal care in early pregnancy (< 20 weeks' gestation) are eligible for inclusion. Study recruitment commenced in February 2012, with an overall participation rate of 76.3%. Study recruitment will continue until December 2018 to achieve the target sample size of 30,000 mother-child pairs. At 30 April 2016, a total of 75,422 questionnaires have been collected, while 14,696 live births have occurred with planned follow-up of cohort children until age 18 years. During the same period a total of 1,053,000 biological samples have been collected from participants, including maternal, paternal and infant blood, cord blood, placenta, umbilical cord, and maternal and infant stool samples. The dataset has been enhanced by record linkage to routine health and administrative records. We plan future record linkage to school enrolment and national examination records.
引用
收藏
页码:337 / 346
页数:10
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