Disturbance of rapid eye movement sleep in spinocerebellar ataxia type 2

被引：39

作者：

Boesch, Sylvia M. ^{[1
]}

Frauscher, Birgit ^{[1
]}

Brandauer, Elisabeth ^{[1
]}

Wenning, Gregor K. ^{[1
]}

Hoegl, Birgit ^{[1
]}

Poewe, Werner ^{[1
]}

机构：

[1] Innsbruck Med Univ, Dept Clin Neurol, A-6020 Innsbruck, Austria

来源：

MOVEMENT DISORDERS | 2006年 / 21卷 / 10期

关键词：

rEM sleep behavior disorder (RBD); REM sleep without atonia (RWA); periodic leg movements (PLM); poly somnography; spinocerebellar ataxia type 2 (SCA2);

D O I：

10.1002/mds.21036

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Five genetically confirmed spinocerebellar ataxia type 2 (SCA2) patients were admitted to our sleep laboratory for two all-night video-polysomnographies. A standard montage was used, including electroencephalography, vertical and horizontal electrooculography, electromyography of mental, submental, and tibialis anterior muscles, and respiratory monitoring. Four of five SCA2 patients had insufficient muscle atonia during rapid eye movement (REM) sleep. All patients exhibited myoclonic jerks during REM sleep, while elaborated behavior was not observed in the video. Abnormal motor control during sleep with periodic leg movements and REM sleep without atonia occurs frequently in SCA2. This finding may reflect a dysfunction of dopaminergic and/or brainstem and cerebellar outflow pathways. (C) 2006 Movement Disorder Society.

引用

页码：1751 / 1754

页数：4

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