Polycystic Ovary Syndrome and Risk of Endometrial Cancer: a Mini-Review

被引：20
作者：
Tokmak, Aytekin [1 ]
Kokanali, Mahmut Kuntay [1 ]
Guzel, Ali Irfan [1 ]
Kara, Aydan [1 ]
Topcu, Hasan Onur [1 ]
Cavkaytar, Sabri [1 ]
机构：
[1] Dr Zekai Tahir Burak Womans Hlth Educ & Res Hosp, Dept Obstet & Gynecol, Ankara, Turkey
来源：
ASIAN PACIFIC JOURNAL OF CANCER PREVENTION | 2014年 / 15卷 / 17期
关键词：
Polycystic ovary syndrome; risk; endometrial cancer; SIGNALING PATHWAYS; SYNDROME PCOS; WOMEN; PROGESTERONE; GROWTH; EXPRESSION; CARCINOMA; ESTROGEN; SURVIVAL; YOUNGER;
D O I：
10.7314/APJCP.2014.15.17.7011
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The polycystic ovary syndrome is the most common endocrinological disorder of reproductive age women with a prevalence of 5 to 8 %. The most common diagnostic criteria used for polycystic ovary syndrome are oligo- or an-ovulation, clinical and/or biochemical signs of hyperandrogenism and polycystic ovaries. Hyperandrogenism results in increased estrogen levels and lack of cyclic progesterone due to anovulation and persistent stimulation of the endometrium may lead to endometrial hyperplasia or adenocarcinoma development. In this mini review, we aimed to evaluate the possible relationship between polycystic ovary syndrome and endometrial cancer.
引用
收藏
页码：7011 / 7014
页数：4
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