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Stability and Hopf bifurcation analysis for an HIV infection model with Beddington-DeAngelis incidence and two delays
被引:7
作者:
Miao, Hui
[1
]
Kang, Chengjun
[1
]
机构:
[1] Shanxi Univ Finance & Econ, Sch Appl Math, Taiyuan 030006, Shanxi, Peoples R China
基金:
中国国家自然科学基金;
关键词:
HIV infection model;
Equilibrium;
Local and global stability;
Lyapunov functional;
Hopf bifurcation;
PARASITES;
D O I:
10.1007/s12190-018-1213-9
中图分类号:
O29 [应用数学];
学科分类号:
070104 ;
摘要:
In this paper, we investigate the dynamical properties for a model of delayed differential equations which describes a virus-immune interaction in vivo. The model has two time delays describing time needed for infection of cell and CTLs generation. The model admits three possible equilibria: infection-free equilibrium, CTL-absent infection equilibrium and CTL-present infection equilibrium. The effect of time delay on stability of the equilibria for the CTL immune response model has been studied.
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页码:265 / 290
页数:26
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