The stimulation of PD-L1-specific cytotoxic T lymphocytes can both directly and indirectly enhance antileukemic immunity

被引：29
作者：
Ahmad, S. M. [1 ]
Svane, I. M. [1 ]
Andersen, M. M. [1 ]
机构：
[1] Copenhagen Univ Hosp, Dept Hematol & Oncol, Ctr Canc Immune Therapy CCIT, Herlev, Denmark
来源：
BLOOD CANCER JOURNAL | 2014年 / 4卷
关键词：
CELL-LINES; EXPRESSION; LEUKEMIA; SUBSET; B7-H1; PD-1;
D O I：
10.1038/bcj.2014.50
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：e230 / e230
页数：3
相关论文
共 15 条
  • [1] Harnessing PD-L1-specific cytotoxic T cells for anti-leukemia immunotherapy to defeat mechanisms of immune escape mediated by the PD-1 pathway
    Ahmad, S. M.
    Larsen, S. K.
    Svane, I. M.
    Andersen, M. H.
    [J]. LEUKEMIA, 2014, 28 (01) : 236 - 238
  • [2] The targeting of immunosuppressive mechanisms in hematological malignancies
    Andersen, M. H.
    [J]. LEUKEMIA, 2014, 28 (09) : 1784 - 1792
  • [3] Coinhibitory molecule PD-1 as a potential target for the immunotherapy of multiple myeloma
    Atanackovic, D.
    Luetkens, T.
    Kroeger, N.
    [J]. LEUKEMIA, 2014, 28 (05) : 993 - 1000
  • [4] Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies
    Berger, Raanan
    Rotem-Yehudar, Rinat
    Slama, Gideon
    Landes, Shimon
    Kneller, Abraham
    Leiba, Merav
    Koren-Michowitz, Maya
    Shimoni, Avichai
    Nagler, Arnon
    [J]. CLINICAL CANCER RESEARCH, 2008, 14 (10) : 3044 - 3051
  • [5] PD-L1 Expression Is Characteristic of a Subset of Aggressive B-cell Lymphomas and Virus-Associated Malignancies
    Chen, Benjamin J.
    Chapuy, Bjoern
    Jing Ouyang
    Sun, Heather H.
    Roemer, Margaretha G. M.
    Xu, Mina L.
    Yu, Hongbo
    Fletcher, Christopher D. M.
    Freeman, Gordon J.
    Shipp, Margaret A.
    Rodig, Scott J.
    [J]. CLINICAL CANCER RESEARCH, 2013, 19 (13) : 3462 - 3473
  • [6] Increased Level of Myeloid-Derived Suppressor Cells, Programmed Death Receptor Ligand 1/Programmed Death Receptor 1, and Soluble CD25 in Sokal High Risk Chronic Myeloid Leukemia
    Christiansson, Lisa
    Soderlund, Stina
    Svensson, Emma
    Mustjoki, Satu
    Bengtsson, Mats
    Simonsson, Bengt
    Olsson-Stromberg, Ulla
    Loskog, Angelica S. I.
    [J]. PLOS ONE, 2013, 8 (01):
  • [7] Dong HD, 1999, NAT MED, V5, P1365
  • [8] False leukemia-lymphoma cell lines: an update on over 500 cell lines
    Drexler, HG
    Dirks, WG
    Matsuo, Y
    MacLeod, RAF
    [J]. LEUKEMIA, 2003, 17 (02) : 416 - 426
  • [9] GOKER E, 1995, LEUKEMIA, V9, P274
  • [10] PD-1/PD-L1 expression in human T-cell leukemia virus type 1 carriers and adult T-cell leukemia/lymphoma patients
    Kozako, T.
    Yoshimitsu, M.
    Fujiwara, H.
    Masamoto, I.
    Horai, S.
    White, Y.
    Akimoto, M.
    Suzuki, S.
    Matsushita, K.
    Uozumi, K.
    Tei, C.
    Arima, N.
    [J]. LEUKEMIA, 2009, 23 (02) : 375 - 382
12