The stimulation of PD-L1-specific cytotoxic T lymphocytes can both directly and indirectly enhance antileukemic immunity

被引：30
作者：
Ahmad, S. M. [1 ]
Svane, I. M. [1 ]
Andersen, M. M. [1 ]
机构：
[1] Copenhagen Univ Hosp, Dept Hematol & Oncol, Ctr Canc Immune Therapy CCIT, Herlev, Denmark
来源：
BLOOD CANCER JOURNAL | 2014年 / 4卷
关键词：
CELL-LINES; EXPRESSION; LEUKEMIA; SUBSET; B7-H1; PD-1;
D O I：
10.1038/bcj.2014.50
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：e230 / e230
页数：3
相关论文
共 15 条
[1]   Harnessing PD-L1-specific cytotoxic T cells for anti-leukemia immunotherapy to defeat mechanisms of immune escape mediated by the PD-1 pathway [J].
Ahmad, S. M. ;
Larsen, S. K. ;
Svane, I. M. ;
Andersen, M. H. .
LEUKEMIA, 2014, 28 (01) :236-238
[2]   The targeting of immunosuppressive mechanisms in hematological malignancies [J].
Andersen, M. H. .
LEUKEMIA, 2014, 28 (09) :1784-1792
[3]   Coinhibitory molecule PD-1 as a potential target for the immunotherapy of multiple myeloma [J].
Atanackovic, D. ;
Luetkens, T. ;
Kroeger, N. .
LEUKEMIA, 2014, 28 (05) :993-1000
[4]   Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies [J].
Berger, Raanan ;
Rotem-Yehudar, Rinat ;
Slama, Gideon ;
Landes, Shimon ;
Kneller, Abraham ;
Leiba, Merav ;
Koren-Michowitz, Maya ;
Shimoni, Avichai ;
Nagler, Arnon .
CLINICAL CANCER RESEARCH, 2008, 14 (10) :3044-3051
[5]   PD-L1 Expression Is Characteristic of a Subset of Aggressive B-cell Lymphomas and Virus-Associated Malignancies [J].
Chen, Benjamin J. ;
Chapuy, Bjoern ;
Jing Ouyang ;
Sun, Heather H. ;
Roemer, Margaretha G. M. ;
Xu, Mina L. ;
Yu, Hongbo ;
Fletcher, Christopher D. M. ;
Freeman, Gordon J. ;
Shipp, Margaret A. ;
Rodig, Scott J. .
CLINICAL CANCER RESEARCH, 2013, 19 (13) :3462-3473
[6]   Increased Level of Myeloid-Derived Suppressor Cells, Programmed Death Receptor Ligand 1/Programmed Death Receptor 1, and Soluble CD25 in Sokal High Risk Chronic Myeloid Leukemia [J].
Christiansson, Lisa ;
Soderlund, Stina ;
Svensson, Emma ;
Mustjoki, Satu ;
Bengtsson, Mats ;
Simonsson, Bengt ;
Olsson-Stromberg, Ulla ;
Loskog, Angelica S. I. .
PLOS ONE, 2013, 8 (01)
[7]  
Dong HD, 1999, NAT MED, V5, P1365
[8]   False leukemia-lymphoma cell lines: an update on over 500 cell lines [J].
Drexler, HG ;
Dirks, WG ;
Matsuo, Y ;
MacLeod, RAF .
LEUKEMIA, 2003, 17 (02) :416-426
[9]  
GOKER E, 1995, LEUKEMIA, V9, P274
[10]   PD-1/PD-L1 expression in human T-cell leukemia virus type 1 carriers and adult T-cell leukemia/lymphoma patients [J].
Kozako, T. ;
Yoshimitsu, M. ;
Fujiwara, H. ;
Masamoto, I. ;
Horai, S. ;
White, Y. ;
Akimoto, M. ;
Suzuki, S. ;
Matsushita, K. ;
Uozumi, K. ;
Tei, C. ;
Arima, N. .
LEUKEMIA, 2009, 23 (02) :375-382
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