Randomized double-blind controlled clinical trial of the blood pressure-lowering effect of fermented milk with Lactococcus lactis: A pilot study

被引：46

作者：

Beltran-Barrientos, Lilia M. ^{[1
]}

Gonzalez-Cordova, Aaron F. ^{[1
]}

Hernandez-Mendoza, Adrian ^{[1
]}

Torres-Inguanzo, Eduardo H. ^{[2
]}

Astiazaran-Garcia, Humberto ^{[1
]}

Esparza-Romero, Julian ^{[1
]}

Vallejo-Cordoba, Belinda ^{[1
]}

机构：

[1] Ctr Invest Alimentac & Desarrollo AC CIAD, Carretera Victoria Km 0-6, Hermosillo 83304, Sonora, Mexico

[2] SC CV Hosp CIMA Hermosillo, Hosp Privado Hermosillo, Hermosillo 83280, Sonora, Mexico

来源：

JOURNAL OF DAIRY SCIENCE | 2018年 / 101卷 / 04期

关键词：

hypertension; Lactococcus lactis; fermented milk; clinical study; functional food; LONG-TERM INTAKE; ANTIHYPERTENSIVE PEPTIDES; BIOACTIVE PEPTIDES; SOUR MILK; HYPERTENSION; RISK; POPULATION; MECHANISMS; PRODUCTS;

D O I：

10.3168/jds.2017-13189

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

The blood pressure-lowering effect of fermented milk with Lactococcus lactis NRRL B-50571 was evaluated in a double-blind randomized controlled clinical trial with prehypertensive subjects. Participants were randomized into 2 groups (n = 18 each group): one group treated with fermented milk with Lactococcus lactis NRRL B-50571 and a control group treated with artificially acidified milk. Results revealed that during daily consumption of fermented milk for 5 wk, systolic [(116.55 +/- 12.26 mmHg vs. 124.77 +/- 11.04 mmHg) and diastolic blood pressure (80.7 +/- 9 vs. 84.5 +/- 8.5 mmHg)] from the fermented milk group was lower than the control group. Additionally, triglyceride, total cholesterol, and low-density lipoprotein in blood serum were lower in the fermented milk group than in the control group. Results demonstrated that daily consumption of fermented milk with Lactococcus lactis (NRRL B-50571) had a blood pressure-lowering effect on prehypertensive subjects. Regular consumption of this product may be used as a potential functional food.

引用

页码：2819 / 2825

页数：7

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