High-dose chemotherapy with autologous peripheral blood stem cell transplantation for metastatic gastric leiomyosarcoma

被引：9
|
作者：
Fetscher, S [1 ]
Brugger, W [1 ]
Bertz, H [1 ]
Krieger, G [1 ]
Kanz, L [1 ]
Mertelsmann, R [1 ]
Lange, W [1 ]
机构：
[1] UNIV TUBINGEN,MED CTR,DEPT INTERNAL MED,DIV HEMATOL & ONCOL,TUBINGEN,GERMANY
来源：
BONE MARROW TRANSPLANTATION | 1997年 / 20卷 / 09期
关键词：
gastrointestinal sarcoma; leiomyosarcoma; soft tissue sarcoma; high-dose chemotherapy; autologous peripheral blood stem cell transplantation;
D O I：
10.1038/sj.bmt.1700970
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
We report a case of metastatic gastrointestinal leiomyosarcoma treated with high-dose combination chemotherapy and autologous peripheral blood stem cell transplantation. After incomplete surgical resection, enteral, peritoneal and hepatic involvement remained, Postoperatively, standard-dose chemotherapy with etoposide, ifosfamide, cisplatin and epirubicin, and high-dose chemotherapy with the same agents (carboplatin replacing cisplatin) was given, Treatment was well tolerated and the patient remains in complete remission at 36+ months, We conclude that high-dose chemotherapy followed by autologous peripheral blood stem cell transplantation may be of use as treatment for inoperable residual disease after resection of the primary lesion in gastrointestinal and other soft tissue sarcomas.
引用
收藏
页码：787 / 788
页数：2
相关论文
共 50 条
  • [41] High-dose chemotherapy followed by autologous and allogeneic peripheral blood stem cell transplantation for recurrent disseminated trilateral retinoblastoma
    Toshihisa Tsuruta
    Yasuo Aihara
    Hitoshi Kanno
    Chikako Kiyotani
    Katsuya Maebayashi
    Masako Sakauchi
    Makiko Osawa
    Hisaichi Fujii
    Osami Kubo
    Yoshikazu Okada
    Child's Nervous System, 2011, 27 : 1019 - 1024
  • [42] Comparison of lenograstim and filgrastim on haematological effects after autologous peripheral blood stem cell transplantation with high-dose chemotherapy
    Kim, IH
    Park, SK
    Suh, OK
    Oh, JM
    CURRENT MEDICAL RESEARCH AND OPINION, 2003, 19 (08) : 753 - 759
  • [43] Fungal Infections in Patients with Solid Tumors Treated with High-Dose Chemotherapy and Autologous Peripheral Blood Stem Cell Transplantation
    J. Montesinos
    C. Sola
    P. Maroto
    R. Salazar
    J. Balmaña
    A. Ramírez
    B. Pardo
    R. Pericás
    M. Gurgui
    J. López-López
    European Journal of Clinical Microbiology and Infectious Diseases, 2001, 20 : 569 - 572
  • [44] Successful Treatment of Bulky Granulocytic Sarcoma of the Retroperitoneum with High-Dose Chemotherapy and Autologous Peripheral Blood Stem Cell Transplantation
    Matsui, Takahiro
    Hidaka, Michihiro
    Kiyokawa, Tetsuyuki
    Murayama, Toshihiko
    Kawano, Fumio
    JOURNAL OF CLINICAL AND EXPERIMENTAL HEMATOPATHOLOGY, 2013, 53 (03) : 234 - 239
  • [45] Fatal pulmonary thromboembolism after a second course of high-dose chemotherapy with autologous peripheral blood stem cell transplantation
    Kounami, S
    Aoyagi, N
    Nakayama, K
    Yoshiyama, M
    Boshi, H
    Sakiyama, M
    Takeuchi, T
    Yoshikawa, N
    PEDIATRIC TRANSPLANTATION, 2003, 7 (05) : 400 - 403
  • [46] Fungal infections in patients with solid tumors treated with high-dose chemotherapy and autologous peripheral blood stem cell transplantation
    Montesinos, J
    Sola, C
    Maroto, P
    Salazar, R
    Balmaña, J
    Ramírez, A
    Pardo, B
    Pericás, R
    Gurgui, M
    López-López, JJ
    EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES, 2001, 20 (08) : 569 - 572
  • [47] High-dose chemotherapy followed by autologous and allogeneic peripheral blood stem cell transplantation for recurrent disseminated trilateral retinoblastoma
    Tsuruta, Toshihisa
    Aihara, Yasuo
    Kanno, Hitoshi
    Kiyotani, Chikako
    Maebayashi, Katsuya
    Sakauchi, Masako
    Osawa, Makiko
    Fujii, Hisaichi
    Kubo, Osami
    Okada, Yoshikazu
    CHILDS NERVOUS SYSTEM, 2011, 27 (06) : 1019 - 1024
  • [48] Therapeutic effects of high-dose chemotherapy with autologous peripheral blood stem cell transplantation for high-risk advanced neuroblastoma
    Mao, Lei
    Xia, Bing
    Yang, Hongliang
    Wang, Yafei
    Yu, Yong
    Wang, Xiaofeng
    Zhao, Zhigang
    Wang, Jingfu
    Li, Jie
    Li, Zhanglin
    Zhao, Qiang
    Yan, Jie
    Zhang, Yizhuo
    BONE MARROW TRANSPLANTATION, 2018, 53 : 738 - 739
  • [49] Tandem high-dose chemotherapy supported by autologous peripheral blood stem cell transplantation for recurrent soft tissue sarcoma
    Kozuka, T
    Kiura, K
    Katayama, H
    Fujii, N
    Ishimaru, F
    Ikeda, K
    Ueoka, H
    Hamasaki, S
    Yoshino, T
    Kashihara, Y
    Date, H
    Tanimoto, M
    Harada, M
    ANTICANCER RESEARCH, 2002, 22 (05) : 2939 - 2944
  • [50] Analysis of pulmonary infections during high-dose chemotherapy (HDC) and peripheral blood stem cell autologous transplantation (PBSCT)
    Sola, C
    Salazar, R
    Maroto, P
    Tabernero, JM
    Valenti, V
    Brunet, J
    Ojeda, B
    Alonso, MC
    Verger, G
    Lopez, JJL
    EUROPEAN JOURNAL OF CANCER, 1997, 33 : 421 - 421
12345