At the time of diagnosis primary cutaneous lymphomas are limited to the skin. T-cell lymphomas represent at least two thirds of all primary cutaneous lymphomas with mycosis fungoides and Sezary syndrome being the most frequent entities. A precise staging based on clinical, histological, immunohistological and molecular biological criteria is crucial for selecting the appropriate therapy. Since curative treatment is only possible in exceptional cases, the aim of any therapy is to achieve healing of the skin lesions, minimizing relapses, preventing progression and maintaining the quality of life. While in early disease stages skin-directed therapy is being used, in later stages systemic treatments become more important. This work aims to provide an overview of established and new therapies for the treatment of mycosis fungoides and Sezary syndrome.
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Department of Dermatology, University of Pennsylvania Health System, Philadelphia, PA 19104Department of Dermatology, University of Pennsylvania Health System, Philadelphia, PA 19104
Kim E.J.
Lin J.
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Department of Dermatology, University of Pennsylvania Health System, Philadelphia, PA 19104Department of Dermatology, University of Pennsylvania Health System, Philadelphia, PA 19104
Lin J.
Junkins-Hopkins J.M.
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Department of Dermatology, University of Pennsylvania Health System, Philadelphia, PA 19104Department of Dermatology, University of Pennsylvania Health System, Philadelphia, PA 19104
Junkins-Hopkins J.M.
Vittorio C.C.
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Department of Dermatology, University of Pennsylvania Health System, Philadelphia, PA 19104Department of Dermatology, University of Pennsylvania Health System, Philadelphia, PA 19104
Vittorio C.C.
Rook A.H.
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Department of Dermatology, University of Pennsylvania Health System, Philadelphia, PA 19104Department of Dermatology, University of Pennsylvania Health System, Philadelphia, PA 19104
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Univ Mediterranee, UMR 1090, TAGC, Case 928,163 Ave Luminy, F-13288 Marseille 09, France
Hop La Concept, Serv Hematol, F-13005 Marseille, FranceUniv Mediterranee, UMR 1090, TAGC, Case 928,163 Ave Luminy, F-13288 Marseille 09, France
Costello, Regis
Farnault, Laure
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Univ Mediterranee, UMR 1090, TAGC, Case 928,163 Ave Luminy, F-13288 Marseille 09, France
Hop La Concept, Serv Hematol, F-13005 Marseille, FranceUniv Mediterranee, UMR 1090, TAGC, Case 928,163 Ave Luminy, F-13288 Marseille 09, France
Farnault, Laure
Bonnet, Nathalie
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Univ Mediterranee, UMR 1090, TAGC, Case 928,163 Ave Luminy, F-13288 Marseille 09, France
Hop Nord Marseille, Serv Dermatol, F-13015 Marseille, FranceUniv Mediterranee, UMR 1090, TAGC, Case 928,163 Ave Luminy, F-13288 Marseille 09, France
Bonnet, Nathalie
Le Treut, Therese
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Hop Nord Marseille, Lab Hematol, F-13015 Marseille, FranceUniv Mediterranee, UMR 1090, TAGC, Case 928,163 Ave Luminy, F-13288 Marseille 09, France
Le Treut, Therese
Poullin, Pascale
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Hop La Concept, Serv Hemaphereses, F-13005 Marseille, FranceUniv Mediterranee, UMR 1090, TAGC, Case 928,163 Ave Luminy, F-13288 Marseille 09, France
Poullin, Pascale
Kahn-Perles, Brigitte
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Univ Mediterranee, UMR 1090, TAGC, Case 928,163 Ave Luminy, F-13288 Marseille 09, FranceUniv Mediterranee, UMR 1090, TAGC, Case 928,163 Ave Luminy, F-13288 Marseille 09, France