Cardiac cell-derived exosomes: changing face of regenerative biology

被引：30

作者：

Kishore, Raj ^{[1
,2
]}

Khan, Mohsin ^{[1
]}

机构：

[1] Temple Univ, Lewis Katz Sch Med, Ctr Translat Med, Philadelphia, PA 19122 USA

[2] Temple Univ, Lewis Katz Sch Med, Dept Pharmacol, Philadelphia, PA 19122 USA

来源：

EUROPEAN HEART JOURNAL | 2017年 / 38卷 / 03期

基金：

美国国家卫生研究院;

关键词：

RANDOMIZED PHASE-1 TRIAL; MYOCARDIAL-INFARCTION; STEM-CELLS; REPAIR;

D O I：

10.1093/eurheartj/ehw324

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

[No abstract available]

引用

页码：212 / 215

页数：4

共 16 条

[1] Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury [J].

Arslan, Fatih ;

Lai, Ruenn Chai ;

Smeets, Mirjam B. ;

Akeroyd, Lars ;

Choo, Andre ;

Aguor, Eissa N. E. ;

Timmers, Leo ;

van Rijen, Harold V. ;

Doevendans, Pieter A. ;

Pasterkamp, Gerard ;

Lim, Sai Kiang ;

de Kleijn, Dominique P. .

STEM CELL RESEARCH, 2013, 10 (03) :301-312

[2] Adult cardiac stem cells are multipotent and support myocardial regeneration [J].

Beltrami, AP ;

Barlucchi, L ;

Torella, D ;

Baker, M ;

Limana, F ;

Chimenti, S ;

Kasahara, H ;

Rota, M ;

Musso, E ;

Urbanek, K ;

Leri, A ;

Kajstura, J ;

Nadal-Ginard, B ;

Anversa, P .

CELL, 2003, 114 (06) :763-776

[3] RETRACTED: Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial (Retracted article. See vol. 393, pg. 1084, 2019) [J].

Bolli, Roberto ;

Chugh, Atul R. ;

D'Amario, Domenico ;

Loughran, John H. ;

Stoddard, Marcus F. ;

Ikram, Sohail ;

Beache, Garth M. ;

Wagner, Stephen G. ;

Leri, Annarosa ;

Hosoda, Toru ;

Sanada, Fumihiro ;

Elmore, Julius B. ;

Goichberg, Polina ;

Cappetta, Donato ;

Solankhi, Naresh K. ;

Fahsah, Ibrahim ;

Rokosh, D. Gregg ;

Slaughter, Mark S. ;

Kajstura, Jan ;

Anversa, Piero .

LANCET, 2011, 378 (9806) :1847-1857

[4] Relative Roles of Direct Regeneration Versus Paracrine Effects of Human Cardiosphere-Derived Cells Transplanted Into Infarcted Mice [J].

Chimenti, Isotta ;

Smith, Rachel Ruckdeschel ;

Li, Tao-Sheng ;

Gerstenblith, Gary ;

Messina, Elisa ;

Giacomello, Alessandro ;

Marban, Eduardo .

CIRCULATION RESEARCH, 2010, 106 (05) :971-U304

[5] Exosomes secreted by cardiosphere-derived cells reduce scarring, attenuate adverse remodelling, and improve function in acute and chronic porcine myocardial infarction [J].

Gallet, Romain ;

Dawkins, James ;

Valle, Jackelyn ;

Simsolo, Eli ;

de Couto, Geoffrey ;

Middleton, Ryan ;

Tseliou, Eleni ;

Luthringer, Daniel ;

Kreke, Michelle ;

Smith, Rachel R. ;

Marban, Linda ;

Ghaleh, Bijan ;

Marban, Eduardo .

EUROPEAN HEART JOURNAL, 2017, 38 (03) :201-211

[6] Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement [J].

Gnecchi, Massimiliano ;

He, Huamei ;

Noiseux, Nicolas ;

Liang, Olin D. ;

Zhang, Lunan ;

Morello, Fulvio ;

Mu, Hui ;

Melo, Luis G. ;

Pratt, Richard E. ;

Ingwall, Joanne S. ;

Dzau, Victor J. .

FASEB JOURNAL, 2006, 20 (06) :661-669

[7] IGF-1-Overexpressing Mesenchymal Stem Cells Accelerate Bone Marrow Stem Cell Mobilization via Paracrine Activation of SDF-1α/CXCR4 Signaling to Promote Myocardial Repair [J].

Haider, Husnain Kh ;

Jiang, Shujia ;

Idris, Niagara M. ;

Ashraf, Muhammad .

CIRCULATION RESEARCH, 2008, 103 (11) :1300-1308

[8] Embryonic Stem Cell-Derived Exosomes Promote Endogenous Repair Mechanisms and Enhance Cardiac Function Following Myocardial Infarction [J].

Khan, Mohsin ;

Nickoloff, Emily ;

Abramova, Tatiana ;

Johnson, Jennifer ;

Verma, Suresh Kumar ;

Krishnamurthy, Prasanna ;

Mackie, Alexander Roy ;

Vaughan, Erin ;

Garikipati, Venkata Naga Srikanth ;

Benedict, Cynthia ;

Ramirez, Veronica ;

Lambers, Erin ;

Ito, Aiko ;

Gao, Erhe ;

Misener, Sol ;

Luongo, Timothy ;

Elrod, John ;

Qin, Gangjian ;

Houser, Steven R. ;

Koch, Walter J. ;

Kishore, Raj .

CIRCULATION RESEARCH, 2015, 117 (01) :52-64

[9] More Than Tiny Sacks Stem Cell Exosomes as Cell-Free Modality for Cardiac Repair [J].

Kishore, Raj ;

Khan, Mohsin .

CIRCULATION RESEARCH, 2016, 118 (02) :330-343

[10] Sustained Delivery of Insulin-Like Growth Factor-1/Hepatocyte Growth Factor Stimulates Endogenous Cardiac Repair in the Chronic Infarcted Pig Heart [J].

Koudstaal, Stefan ;

Bastings, Maartje M. C. ;

Feyen, Dries A. M. ;

Waring, Cheryl D. ;

van Slochteren, Frebus J. ;

Dankers, Patricia Y. W. ;

Torella, Daniele ;

Sluijter, Joost P. G. ;

Nadal-Ginard, Bernardo ;

Doevendans, Pieter A. ;

Ellison, Georgina M. ;

Chamuleau, Steven A. J. .

JOURNAL OF CARDIOVASCULAR TRANSLATIONAL RESEARCH, 2014, 7 (02) :232-241

← 1 2 →