Iterative Iodocyclization: Total Synthesis of Polyrhacitide B

被引：15
作者：
Mohapatra, Debendra K. [1 ]
Krishnarao, P. Sivarama [1 ]
Bhimireddy, Eswar [1 ]
Yadav, Jhillu S. [1 ]
机构：
[1] CSIR Indian Inst Chem Technol, Nat Prod Chem Div, Hyderabad 500007, Andhra Pradesh, India
来源：
SYNTHESIS-STUTTGART | 2014年 / 46卷 / 12期
关键词：
natural products; total synthesis; iodine-catalyzed cyclization; asymmetric allylation; iodocarbonate cyclization; oxidative cleavage; STEREOSELECTIVE TOTAL-SYNTHESIS; CRYPTOCARYA-LATIFOLIA; ALPHA-PYRONES; SECONDARY ALCOHOLS; ALDEHYDES; 5,6-DIHYDRO-ALPHA-PYRONES; DERIVATIVES; OXIDATION; CONCISE; KETONES;
D O I：
10.1055/s-0033-1341154
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A highly stereoselective total synthesis of polyrhacitide B is reported. Key reactions are an iodocyclization protocol developed in our group, the Maruoka asymmetric allylation, the Bartlett-Smith iodocarbonate cyclization, and iodolactonization.
引用
收藏
页码：1639 / 1647
页数：9
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