Iterative Iodocyclization: Total Synthesis of Polyrhacitide B

被引：15

作者：

Mohapatra, Debendra K. ^{[1
]}

Krishnarao, P. Sivarama ^{[1
]}

Bhimireddy, Eswar ^{[1
]}

Yadav, Jhillu S. ^{[1
]}

机构：

[1] CSIR Indian Inst Chem Technol, Nat Prod Chem Div, Hyderabad 500007, Andhra Pradesh, India

来源：

SYNTHESIS-STUTTGART | 2014年 / 46卷 / 12期

关键词：

natural products; total synthesis; iodine-catalyzed cyclization; asymmetric allylation; iodocarbonate cyclization; oxidative cleavage; STEREOSELECTIVE TOTAL-SYNTHESIS; CRYPTOCARYA-LATIFOLIA; ALPHA-PYRONES; SECONDARY ALCOHOLS; ALDEHYDES; 5,6-DIHYDRO-ALPHA-PYRONES; DERIVATIVES; OXIDATION; CONCISE; KETONES;

D O I：

10.1055/s-0033-1341154

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly stereoselective total synthesis of polyrhacitide B is reported. Key reactions are an iodocyclization protocol developed in our group, the Maruoka asymmetric allylation, the Bartlett-Smith iodocarbonate cyclization, and iodolactonization.

引用

页码：1639 / 1647

页数：9

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