Second Harmonic Microscopic Imaging and Spectroscopic Characterization in Prostate Pathological Tissue

被引：5

作者：

Huang, Yanyue ^{[1
]}

Zhuang, Zhengfei ^{[2
]}

机构：

[1] S China Normal Univ, Lab Photon Informat Technol, Guangzhou 510631, Guangdong, Peoples R China

[2] S China Normal Univ, Coll Biophoton, Lab Photon Chinese Med, Guangzhou 510631, Guangdong, Peoples R China

来源：

SCANNING | 2014年 / 36卷 / 03期

基金：

高等学校博士学科点专项科研基金; 中国国家自然科学基金;

关键词：

second harmonic generation; prostatic hyperplasia; prostate cancer; wavelength sensitivity; GENERATION; COLLAGEN;

D O I：

10.1002/sca.21116

中图分类号：

TH7 [仪器、仪表];

学科分类号：

0804 ; 080401 ; 081102 ;

摘要：

Second harmonic microscopic imaging and spectroscopy technology has become a powerful tool for biomedical studies, especially in cancer research. In this paper, second harmonic generation in benign prostatic hyperplasia (BPH) and prostate cancer (PC) tissues in mouse model (C57BL6) have been reported. Excitated samples with different wavelength near-infrared laser from 780 to 850 nm we found that second harmonic signals from BPH nuclei stronger than that from PC, and a wavelength sensitivity was also observed in this experiment. Providing useful help for prostate malignancy diagnosis and identifying tissue components on clinic. (C) 2013 Wiley Periodicals, Inc.

引用

页码：334 / 337

页数：4

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