Interactions between enteropathogenic Escherichia coli and host epithelial cells

被引：200
作者：
Donnenberg, MS
Kaper, JB
Finlay, BB
机构：
[1] UNIV MARYLAND,SCH MED,DEPT MED,CTR VACCINE DEV,BALTIMORE,MD 21201
[2] UNIV BRITISH COLUMBIA,BIOTECHNOL LAB,VANCOUVER,BC V6T 1Z3,CANADA
[3] UNIV BRITISH COLUMBIA,DEPT BIOCHEM & MOL BIOL,VANCOUVER,BC V6T 1Z3,CANADA
[4] UNIV BRITISH COLUMBIA,DEPT IMMUNOL & MICROBIOL,VANCOUVER,BC V6T 1Z3,CANADA
来源：
TRENDS IN MICROBIOLOGY | 1997年 / 5卷 / 03期
关键词：
D O I：
10.1016/S0966-842X(97)01000-7
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The pathogenesis of enteropathogenic Escherichia coli (EPEC) infection is emerging as a paradigm for a multistage microorganism-host cell interaction. Both type IV fimbriae and a type III secretion apparatus play principal roles in interactions between the bacteria and host cells. Recent data suggest that bacteria-induced signal transduction activates the receptor that allows tenacious adherence of the bacteria to the host cell surface.
引用
收藏
页码：109 / 114
页数：6
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