Psoriasis and comorbid diseases Implications for management

被引:144
作者
Takeshita, Junko [1 ,2 ]
Grewal, Sungat [1 ]
Langan, Sinead M. [4 ,5 ]
Mehta, Nehal N. [6 ]
Ogdie, Alexis [2 ,3 ]
Van Voorhers, Abby S. [7 ]
Gelfand, Joel M. [1 ,2 ]
机构
[1] Univ Penn, Perelman Sch Med, Dept Dermatol, Philadelphia, PA 19104 USA
[2] Univ Penn, Ctr Clin Epidemiol & Biostat, Perelman Sch Med, Dept Epidemiol & Biostat, Philadelphia, PA 19104 USA
[3] Univ Penn, Perelman Sch Med, Div Rheumatol, Philadelphia, PA 19104 USA
[4] London Sch Hyg & Trop Med, London, England
[5] St Johns Inst Dermatol, London, England
[6] NHLBI, Bldg 10, Bethesda, MD 20892 USA
[7] Eastern Virginia Med Sch, Dept Dermatol, Norfolk, VA 23501 USA
基金
美国国家卫生研究院;
关键词
cardiovascular disease; chronic kidney disease; comorbidities; Crohn's disease; depression; infection; lymphoma; metabolic syndrome; nonalcoholic fatty liver disease; psoriasis; psoriatic arthritis; screening; vaccination; POPULATION-BASED-COHORT; FACTOR-ALPHA THERAPY; CARDIOVASCULAR RISK-FACTORS; NECROSIS-FACTOR INHIBITORS; SQUAMOUS-CELL CARCINOMA; HEPATITIS-B-VIRUS; NATIONAL-PSORIASIS; RHEUMATOID-ARTHRITIS; BIOLOGIC THERAPY; TREATMENT RECOMMENDATIONS;
D O I
10.1016/j.jaad.2016.07.065
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
As summarized in the first article in this continuing medical education series, the currently available epidemiologic data suggest that psoriasis may be a risk factor for cardiometabolic disease. Emerging data also suggest associations between psoriasis and other comorbidities beyond psoriatic arthritis, including chronic kidney disease, inflammatory bowel disease, hepatic disease, certain malignancies, infections, and mood disorders. Recognizing the comorbid disease burden of psoriasis is essential for ensuring comprehensive care of patients with psoriasis. The clinical implications of the comorbid diseases that are associated with psoriasis and recommendations for clinical management are reviewed in this article.
引用
收藏
页码:393 / 403
页数:11
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