Prevalence and risk factors of lower limb amputations in patients with diabetic foot ulcers: A systematic review and meta-analysis

被引：58

作者：

Rodrigues, Beverly T. ^{[1
]}

Vangaveti, Venkat N. ^{[1
]}

Urkude, Ravindra ^{[2
]}

Biros, Erik ^{[1
]}

Malabu, Usman H. ^{[1
,3
]}

机构：

[1] James Cook Univ, Coll Med & Dent, Translat Res Endocrinol & Diabet, Douglas, Qld, Australia

[2] Townsville Univ Hosp, Dept Neurol, Douglas, Qld, Australia

[3] Townsville Univ Hosp, Dept Diabet & Endocrinol, Douglas, Qld, Australia

来源：

DIABETES & METABOLIC SYNDROME-CLINICAL RESEARCH & REVIEWS | 2022年 / 16卷 / 02期

关键词：

Diabetic foot ulcers; Amputations; Prevalence; Risk factors; LOWER-EXTREMITY AMPUTATION; MELLITUS; CARE; INDIVIDUALS; NEPHROPATHY; PREDICTORS; MANAGEMENT; ULCERATION; MORTALITY; SURVIVAL;

D O I：

10.1016/j.dsx.2022.102397

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background and aims: The study aimed at determining prevalence and risk factors (RFs) of diabetic lower limb amputations (LLAs). Methods: Electronic databases including PubMed, Medline, Web of Science, and Cochrane Library were searched from January 2003 to April 2021. Results: Sixteen full- text published studies were reviewed. The prevalence of LLAs stood as high as 66%, with a combined prevalence of 19% (95% CI 10-29) using the random-effects model. The most prominent RFs for LLA were duration of diabetes mellitus (DM), age, renal impairment, and ethnic minority. Amongst Australians, Indigenous background is strongly associated with increased risk of the diabetic foot (DF) LLA. Conclusions: LLAs are considerably prevalent amongst patients with the DF and occur at even higher rates in patients with multimorbidity. (C) 2022 Diabetes India. Published by Elsevier Ltd. All rights reserved.

引用

页数：8

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