Risk of Non-cutaneous Cancers in Individuals with Basal Cell Carcinoma: A Population-based Cohort Study

被引：3

作者：

Kuru, Hanna ^{[1
,2
]}

Jokelainen, Jari ^{[3
,4
]}

Tasanen, Kaisa ^{[1
,2
]}

Huilaja, Laura ^{[1
,2
,5
]}

机构：

[1] Univ Hosp Oulu, Dept Dermatol, Oulu, Finland

[2] Univ Oulu, Med Res Ctr, PEDEGO Res Grp, Oulu, Finland

[3] Univ Oulu, Fac Med, Infrastructure Populat Studies, Northern Finland Birth Cohorts,Arctic Biobank, Oulu, Finland

[4] Oulu Univ Hosp, Unit Gen Practice, Oulu, Finland

[5] Oulu Univ Hosp, Dept Dermatol, PB20, FL-90029 Oulu, Finland

来源：

ACTA DERMATO-VENEREOLOGICA | 2022年 / 102卷

关键词：

basal cell carcinoma; non-melanoma skin cancer; NONMELANOMA SKIN-CANCER; 2ND PRIMARY CANCERS; VITAMIN-D; SUN EXPOSURE; DIAGNOSIS; EPIDEMIOLOGY; MALIGNANCIES; MORTALITY; PROSTATE; TRENDS;

D O I：

10.2340/actadv.v102.4451

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Evidence of the association between a personal history of basal cell carcinoma and the risk of non-cutaneous malignancies is conflicting. The aim of this study was to retrospectively clarify the risk of non-cutaneous cancers in individuals with basal cell carcinoma using nationwide Finnish registry data for 96,304 patients and 394,503 randomly selected population controls. In this study, individuals with basal cell carcinoma have an increased risk of other cancers (odds ratio (OR) 1.38; 95% confidence interval (95% CI) 1.36-1.40). The risk was most prominent for lip cancer (OR 5.29; 95% CI 4.50-6.21), mycosis fungoides (OR 3.13; 95% CI 2.31-4.23) and soft tissue cancers (OR 2.77; 95% CI 2.43-3.16). In age-adjusted model, men had higher risk of cancers overall compared with women (p < 0.05). In conclusion, the study found increased overall cancer risk among patients with basal cell carcinoma compared with randomly selected population controls.

引用

页数：6

共 40 条

[1] Basal cell carcinoma: an emerging epidemic in women in Iceland [J].

Adalsteinsson, J. A. ;

Ratner, D. ;

Olafsdottir, E. ;

Grant-Kels, J. ;

Ungar, J. ;

Silverberg, J., I ;

Kristjansson, A. K. ;

Jonasson, J. G. ;

Tryggvadottir, L. .

BRITISH JOURNAL OF DERMATOLOGY, 2020, 183 (05) :847-856

[2] The epidemiology of UV induced skin cancer [J].

Armstrong, BK ;

Kricker, A .

JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY, 2001, 63 (1-3) :8-18

[3] Trends in the incidence of nonmelanoma skin cancer in Denmark 1978-2007: rapid incidence increase among young Danish women [J].

Birch-Johansen, Fatima ;

Jensen, Allan ;

Mortensen, Lone ;

Olesen, Anne Braae ;

Kjaer, Susanne K. .

INTERNATIONAL JOURNAL OF CANCER, 2010, 127 (09) :2190-2198

[4] Basal cell carcinoma and risk of subsequent malignancies: A cancer registry-based study in southwest England [J].

Bower, CPR ;

Lear, JT ;

Bygrave, S ;

Etherington, D ;

Harvey, I ;

Archer, CB .

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2000, 42 (06) :988-991

[5] Second primary cancers in patients with skin cancer: a population-based study in Northern Ireland [J].

Cantwell, M. M. ;

Murray, L. J. ;

Catney, D. ;

Donnelly, D. ;

Autier, P. ;

Boniol, M. ;

Fox, C. ;

Middleton, R. J. ;

Dolan, O. M. ;

Gavin, A. T. .

BRITISH JOURNAL OF CANCER, 2009, 100 (01) :174-177

[6] Nonmelanoma skin cancer and risk for subsequent malignancy [J].

Chen, Jiping ;

Ruczinski, Ingo ;

Jorgensen, Timothy J. ;

Yenokyan, Gayane ;

Yao, Yin ;

Alani, Rhoda ;

Liegeois, Nanette J. ;

Hoffman, Sandra C. ;

Hoffman-Bolton, Judith ;

Strickland, Paul T. ;

Helzlsouer, Kathy J. ;

Alberg, Anthony J. .

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2008, 100 (17) :1215-1222

[7] Decreased risk of prostate cancer after skin cancer diagnosis: A protective role of ultraviolet radiation? [J].

de Vries, Esther ;

Soerjomataram, Isabelle ;

Houterman, Saskia ;

Louwman, Marieke W. J. ;

Coebergh, Jan Willem W. .

AMERICAN JOURNAL OF EPIDEMIOLOGY, 2007, 165 (08) :966-972

[8] Trends in Basal Cell Carcinoma Incidence Rates: A 37-Year Dutch Observational Study [J].

Flohil, Sophie C. ;

Seubring, Inge ;

van Rossum, Michelle M. ;

Coebergh, Jan-Willem W. ;

de Vries, Esther ;

Nijsten, Tamar .

JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2013, 133 (04) :913-918

[9] Association of basal cell skin cancers with other cancers (United States) [J].

Friedman, GD ;

Tekawa, IS .

CANCER CAUSES & CONTROL, 2000, 11 (10) :891-897

[10] Risk for subsequent cancer after diagnosis of basal-cell carcinoma - A population-based, epidemiologic study [J].

Frisch, M ;

Hjalgrim, H ;

Olsen, JH ;

Melbye, M .

ANNALS OF INTERNAL MEDICINE, 1996, 125 (10) :815-+

← 1 2 3 4 →