An elegant synthetic route to 3-cyano-5,6-dihydro-2-ethoxy-4-phenyl-pyrido[2,3-α]carbazoles

被引:6
作者
Danish, IA [1 ]
Prasad, KJR [1 ]
机构
[1] Bharathiar Univ, Dept Chem, Coimbatore 641046, Tamil Nadu, India
来源
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES | 2004年 / 59卷 / 01期
关键词
1-oxo-1,2,3,4-tetrahydrocarbazoles; 2-benzylidene-1-oxo-1,2,3,4-tetrahydrocarbazoles; aldol condensation; malononitrile; sodium hydride;
D O I
10.1515/znb-2004-0115
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
2-Benzylidene-1-oxo-1,2,3,4-tetrahydrocarbazoles (1a-e) obtained from the corresponding 1-oxo-1,2,3,4-tetrahydrocarbazoles on reaction with malononitrile in dry benzene with sodium hydride afforded 3-cyano-5,6-dihydro-2-ethoxy-4-phenyl-pyrido[2,3-a]carbazoles (2a-e) in good yields. A plausible mechanism for the formation of the title compound has been proposed and all the compounds were characterised by IR, NMR, mass spectral methods and elemental analysis.
引用
收藏
页码:106 / 108
页数:3
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