Two-stage exchange remains the gold standard for treatment of peri-prosthetic joint infection after total hip replacement (THR). In the first stage, all components and associated cement if present are removed, an aggressive debridement is undertaken including a complete synovectomy, and an antibiotic-loaded cement spacer is put in place. Patients are then treated with six weeks of parenteral antibiotics, followed by an 'antibiotic free period' to help ensure the infection has been eradicated. If the clinical evaluation and serum inflammatory markers suggest the infection has resolved, then the second stage can be completed, which involves removal of the cement spacer, repeat debridement, and placement of a new THR.
机构:Thomas Jefferson Univ Hosp, Rothman Inst, Dept Orthoped Surg, Philadelphia, PA 19107 USA
Azzam, Khalid A.
;
Seeley, Mark
论文数: 0引用数: 0
h-index: 0
机构:Thomas Jefferson Univ Hosp, Rothman Inst, Dept Orthoped Surg, Philadelphia, PA 19107 USA
Seeley, Mark
;
Ghanem, Elie
论文数: 0引用数: 0
h-index: 0
机构:Thomas Jefferson Univ Hosp, Rothman Inst, Dept Orthoped Surg, Philadelphia, PA 19107 USA
Ghanem, Elie
;
Austin, Matthew S.
论文数: 0引用数: 0
h-index: 0
机构:Thomas Jefferson Univ Hosp, Rothman Inst, Dept Orthoped Surg, Philadelphia, PA 19107 USA
Austin, Matthew S.
;
Purtill, James J.
论文数: 0引用数: 0
h-index: 0
机构:Thomas Jefferson Univ Hosp, Rothman Inst, Dept Orthoped Surg, Philadelphia, PA 19107 USA
Purtill, James J.
;
Parvizi, Javad
论文数: 0引用数: 0
h-index: 0
机构:
Thomas Jefferson Univ Hosp, Rothman Inst, Dept Orthoped Surg, Philadelphia, PA 19107 USAThomas Jefferson Univ Hosp, Rothman Inst, Dept Orthoped Surg, Philadelphia, PA 19107 USA
机构:
Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Orthopaed Surg, Boston, MA 02115 USAHarvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Orthopaed Surg, Boston, MA 02115 USA
Bedair, Hany
;
Ting, Nicholas
论文数: 0引用数: 0
h-index: 0
机构:
Rush Univ, Med Ctr, Dept Orthopaed Surg, Chicago, IL 60612 USAHarvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Orthopaed Surg, Boston, MA 02115 USA
Ting, Nicholas
;
Bozic, Kevin J.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calif San Francisco, Dept Orthopaed Surg, Philip R Lee Inst Hlth Policy, San Francisco, CA USAHarvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Orthopaed Surg, Boston, MA 02115 USA
Bozic, Kevin J.
;
Della Valle, Craig J.
论文数: 0引用数: 0
h-index: 0
机构:
Rush Univ, Med Ctr, Dept Orthopaed Surg, Chicago, IL 60612 USAHarvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Orthopaed Surg, Boston, MA 02115 USA
Della Valle, Craig J.
;
Sporer, Scott M.
论文数: 0引用数: 0
h-index: 0
机构:
Rush Univ, Med Ctr, Dept Orthopaed Surg, Chicago, IL 60612 USAHarvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Orthopaed Surg, Boston, MA 02115 USA
机构:
Department of Orthopaedic and Traumatologic Sciences, University of Insubria, VareseDepartment of Orthopaedic and Traumatologic Sciences, University of Insubria, Varese
D'Angelo F.
;
Negri L.
论文数: 0引用数: 0
h-index: 0
机构:
Department of Orthopaedic and Traumatologic Sciences, University of Insubria, VareseDepartment of Orthopaedic and Traumatologic Sciences, University of Insubria, Varese
Negri L.
;
Binda T.
论文数: 0引用数: 0
h-index: 0
机构:
Department of Orthopaedic and Traumatologic Sciences, University of Insubria, VareseDepartment of Orthopaedic and Traumatologic Sciences, University of Insubria, Varese
Binda T.
;
Zatti G.
论文数: 0引用数: 0
h-index: 0
机构:
Department of Orthopaedic and Traumatologic Sciences, University of Insubria, VareseDepartment of Orthopaedic and Traumatologic Sciences, University of Insubria, Varese
Zatti G.
;
Cherubino P.
论文数: 0引用数: 0
h-index: 0
机构:
Department of Orthopaedic and Traumatologic Sciences, University of Insubria, VareseDepartment of Orthopaedic and Traumatologic Sciences, University of Insubria, Varese
机构:Thomas Jefferson Univ Hosp, Rothman Inst, Dept Orthoped Surg, Philadelphia, PA 19107 USA
Azzam, Khalid A.
;
Seeley, Mark
论文数: 0引用数: 0
h-index: 0
机构:Thomas Jefferson Univ Hosp, Rothman Inst, Dept Orthoped Surg, Philadelphia, PA 19107 USA
Seeley, Mark
;
Ghanem, Elie
论文数: 0引用数: 0
h-index: 0
机构:Thomas Jefferson Univ Hosp, Rothman Inst, Dept Orthoped Surg, Philadelphia, PA 19107 USA
Ghanem, Elie
;
Austin, Matthew S.
论文数: 0引用数: 0
h-index: 0
机构:Thomas Jefferson Univ Hosp, Rothman Inst, Dept Orthoped Surg, Philadelphia, PA 19107 USA
Austin, Matthew S.
;
Purtill, James J.
论文数: 0引用数: 0
h-index: 0
机构:Thomas Jefferson Univ Hosp, Rothman Inst, Dept Orthoped Surg, Philadelphia, PA 19107 USA
Purtill, James J.
;
Parvizi, Javad
论文数: 0引用数: 0
h-index: 0
机构:
Thomas Jefferson Univ Hosp, Rothman Inst, Dept Orthoped Surg, Philadelphia, PA 19107 USAThomas Jefferson Univ Hosp, Rothman Inst, Dept Orthoped Surg, Philadelphia, PA 19107 USA
机构:
Harvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Orthopaed Surg, Boston, MA 02115 USAHarvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Orthopaed Surg, Boston, MA 02115 USA
Bedair, Hany
;
Ting, Nicholas
论文数: 0引用数: 0
h-index: 0
机构:
Rush Univ, Med Ctr, Dept Orthopaed Surg, Chicago, IL 60612 USAHarvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Orthopaed Surg, Boston, MA 02115 USA
Ting, Nicholas
;
Bozic, Kevin J.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Calif San Francisco, Dept Orthopaed Surg, Philip R Lee Inst Hlth Policy, San Francisco, CA USAHarvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Orthopaed Surg, Boston, MA 02115 USA
Bozic, Kevin J.
;
Della Valle, Craig J.
论文数: 0引用数: 0
h-index: 0
机构:
Rush Univ, Med Ctr, Dept Orthopaed Surg, Chicago, IL 60612 USAHarvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Orthopaed Surg, Boston, MA 02115 USA
Della Valle, Craig J.
;
Sporer, Scott M.
论文数: 0引用数: 0
h-index: 0
机构:
Rush Univ, Med Ctr, Dept Orthopaed Surg, Chicago, IL 60612 USAHarvard Univ, Massachusetts Gen Hosp, Sch Med, Dept Orthopaed Surg, Boston, MA 02115 USA
机构:
Department of Orthopaedic and Traumatologic Sciences, University of Insubria, VareseDepartment of Orthopaedic and Traumatologic Sciences, University of Insubria, Varese
D'Angelo F.
;
Negri L.
论文数: 0引用数: 0
h-index: 0
机构:
Department of Orthopaedic and Traumatologic Sciences, University of Insubria, VareseDepartment of Orthopaedic and Traumatologic Sciences, University of Insubria, Varese
Negri L.
;
Binda T.
论文数: 0引用数: 0
h-index: 0
机构:
Department of Orthopaedic and Traumatologic Sciences, University of Insubria, VareseDepartment of Orthopaedic and Traumatologic Sciences, University of Insubria, Varese
Binda T.
;
Zatti G.
论文数: 0引用数: 0
h-index: 0
机构:
Department of Orthopaedic and Traumatologic Sciences, University of Insubria, VareseDepartment of Orthopaedic and Traumatologic Sciences, University of Insubria, Varese
Zatti G.
;
Cherubino P.
论文数: 0引用数: 0
h-index: 0
机构:
Department of Orthopaedic and Traumatologic Sciences, University of Insubria, VareseDepartment of Orthopaedic and Traumatologic Sciences, University of Insubria, Varese