Copper-catalyzed 1,3-aminoazidation of arylcyclopropanes: a facile access to 1,3-diamine derivatives

被引：36

作者：

Wang, Lihong ^{[1
]}

Wang, Xiaomin ^{[1
]}

Zhang, Ge ^{[1
]}

Yang, Shengbiao ^{[1
]}

Li, Yan ^{[1
]}

Zhang, Qian ^{[1
,2
]}

机构：

[1] Northeast Normal Univ, Dept Chem, Jilin Prov Key Lab Organ Funct Mol Design & Synth, Changchun 130024, Jilin, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, 345 Lingling Lu, Shanghai 200032, Peoples R China

来源：

ORGANIC CHEMISTRY FRONTIERS | 2019年 / 6卷 / 16期

基金：

中国国家自然科学基金;

关键词：

DONOR-ACCEPTOR CYCLOPROPANES; STEREOSELECTIVE-SYNTHESIS; SYNTHETIC METHODS; AMMONIUM-NITRATE; CU-II; IMINES; ACTIVATION; AMINATION; RING; AMINOMETHYLAMINATION;

D O I：

10.1039/c9qo00638a

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Copper-catalyzed 1,3-aminoazidation of arylcyclopropanes with N-fluorobenzenesulfonimide (NFSI) and trimethylsilyl azide (TMSN3) has been established, facilely and efficiently affording a wide range of 1,3-diamine derivatives in moderate to good yields under mild conditions. It represents the first example of 1,3-diamination of cyclopropanes by simultaneously introducing two different nitrogen sources, which might provide a new route to ring-opening 1,3-bisfunctionalization of cyclopropanes.

引用

页码：2934 / 2938

页数：5

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