Acute effects of strength and endurance exercise on serum BDNF and IGF-1 levels in older men

被引：47

作者：

Arazi, Hamid ^{[1
]}

Babaei, Parvin ^{[2
,3
]}

Moghimi, Makan ^{[4
]}

Asadi, Abbas ^{[5
]}

机构：

[1] Univ Guilan, Fac Sport Sci, Dept Exercise Physiol, Rasht, Iran

[2] Guilan Univ Med Sci, Cellular & Mol Res Ctr, Rasht, Iran

[3] Guilan Univ Med Sci, Dept Physiol, Rasht, Iran

[4] Islamic Azad Univ, Rasht Branch, Dept Sport Sci, Rasht, Iran

[5] Payame Noor Univ, Dept Phys Educ & Sport Sci, Tehran, Iran

来源：

BMC GERIATRICS | 2021年 / 21卷 / 01期

关键词：

Brain aging; Neurotrophic factor; Physical exercise;

D O I：

10.1186/s12877-020-01937-6

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

BackgroundRegarding an important effects of physical exercise on brain function in elders, the aim of this study was to examine the effects of strength and endurance exercise on brain neurobiological factors in older men.MethodsThirty older men volunteered to participate in this study and were randomly assigned to strength, endurance and control groups. The subjects in strength group performed two circuits of resistance exercise (6 exercises with 10 repetition of 65-70% of one repetition maximum), while endurance group performed 30min running with 65-70% of maximal heart rate. Blood was obtained pre and post-exercise to determine changes in serum BDNF, IGF-1 and platelets.ResultsAfter exercise, both the strength and endurance groups showed significant increases in serum BDNF and IGF-1 concentrations and platelets at post-exercise and in comparison to control group (p<0.05). In addition, no statistically significant differences were detected between the strength and endurance groups at post-exercise.ConclusionOur findings indicate that both the strength and endurance interventions are effective in elevating BDNF, IGF-1, and platelets, without significant differences between them.

引用

页数：8