Influence of wave-front sampling in adaptive optics retinal imaging

被引:5
作者
Laslandes, Marie [1 ]
Salas, Matthias [1 ]
Hitzenberger, Christoph K. [1 ]
Pircher, Michael [1 ]
机构
[1] Med Univ Vienna, Ctr Med Phys & Biomed Engn, Waehringer Guertel 18-20, A-1090 Vienna, Austria
来源
BIOMEDICAL OPTICS EXPRESS | 2017年 / 8卷 / 02期
基金
奥地利科学基金会;
关键词
SCANNING LASER OPHTHALMOSCOPE; HUMAN EYE; COHERENCE TOMOGRAPHY; IN-VIVO; HIGH-RESOLUTION; SENSOR; ABERRATIONS; SYSTEM; PHOTORECEPTORS; QUALITY;
D O I
10.1364/BOE.8.001083
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A wide range of sampling densities of the wave-front has been used in retinal adaptive optics (AO) instruments, compared to the number of corrector elements. We developed a model in order to characterize the link between number of actuators, number of wave-front sampling points and AO correction performance. Based on available data from aberration measurements in the human eye, 1000 wave-fronts were generated for the simulations. The AO correction performance in the presence of these representative aberrations was simulated for different deformable mirror and Shack Hartmann wave-front sensor combinations. Predictions of the model were experimentally tested through in vivo measurements in 10 eyes including retinal imaging with an AO scanning laser ophthalmoscope. According to our study, a ratio between wavefront sampling points and actuator elements of 2 is sufficient to achieve high resolution in vivo images of photoreceptors. (C) 2017 Optical Society of America
引用
收藏
页码:1083 / 1100
页数:18
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