Enantiomeric separation with sulfobutyl ether-β-cyclodextrin as chiral additive by capillary electrophoresis

被引：0

作者：

Ruan, ZQ ^{[1
]}

Lu, HJ ^{[1
]}

Ou, QY ^{[1
]}

机构：

[1] Chinese Acad Sci, Lanzhou Inst Chem Phys, Lanzhou 730000, Peoples R China

来源：

CHINESE JOURNAL OF ANALYTICAL CHEMISTRY | 2000年 / 28卷 / 02期

关键词：

capillary electrophoresis; sulfobutyl ether-beta-cyclodextrin; enantiomeric separation;

D O I：

暂无

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Enantiomeric separations of chiral drugs with an anionic chiral resolving agent, sulfobutyl ether beta-cyclodextrin( SBE-beta-CD) with average substitute degree 3.8, employed as chiral additive by capillary electrophoresis were achieved. The effects of pH of background electrolyte, the concentration of sulfobutyl ether-beta-cyclodextrin on chiral separation were investigated. The enantiomeric separation of six basic and two acidic chiral drugs was accomplished. Sulfobutyl ether-beta-cyclodextrin was proved to be a good chiral selector having itself electrophoretic mobility.

引用

页码：168 / 171

页数：4

共 5 条

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