5-HT2C receptor modulation and the treatment of obesity

被引:36
|
作者
Bickerdike, MJ [1 ]
Vickers, SP [1 ]
Dourish, CT [1 ]
机构
[1] Cerebrus PLC, Wokingham RG41 5UA, England
来源
DIABETES OBESITY & METABOLISM | 1999年 / 1卷 / 04期
关键词
D O I
10.1046/j.1463-1326.1999.00037.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:207 / 214
页数:8
相关论文
共 50 条
  • [11] Epilepsy and obesity in serotonin 5-HT2C receptor mutant mice
    Heisler, LK
    Chu, HM
    Tecott, LH
    ADVANCES IN SEROTONIN RECEPTOR RESEARCH: MOLECULAR BIOLOGY, SIGNAL TRANSDUCTION, AND THERAPEUTICS, 1998, 861 : 74 - 78
  • [12] Dynamic 5-HT2C Receptor Editing in a Mouse Model of Obesity
    Schellekens, Harriet
    Clarke, Gerard
    Jeffery, Ian B.
    Dinan, Timothy G.
    Cryan, John F.
    PLOS ONE, 2012, 7 (03):
  • [13] Discovery, SAR and biology of 5-HT2C receptors for the treatment of obesity
    Smith, BM
    Smith, J
    Tsai, JH
    Schultz, JA
    Gilson, C
    Chen, R
    Estrada, S
    Park, D
    Prieto, E
    Sengupta, D
    Saldana, H
    Thomsen, W
    Kevin, W
    Creehan, K
    Gonzalez, L
    Menzaghi, F
    Bjenning, C
    Beeley, N
    Webb, RR
    Behan, D
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2005, 229 : U159 - U159
  • [14] Targeting the 5-HT2C Receptor in Biological Context and the Current State of 5-HT2C Receptor Ligand Development
    Wold, Eric A.
    Wild, Christopher T.
    Cunningham, Kathryn A.
    Zhou, Jia
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2019, 19 (16) : 1381 - 1398
  • [15] 5-HT2C receptor and leptin polymorphisms, obesity and metabolic syndrome in schizophrenia
    Yevtushenko, Olga
    Cooper, Stephen
    O'Neill, Ryan
    Doherty, Jeniffer
    Reynolds, Gavin
    AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS, 2006, 141B (07) : 789 - 789
  • [16] 5-HT2C receptor and leptin polymorphisms, obesity and metabolic syndrome in schizophrenia
    Yevtushenko, O.
    Cooper, S. J.
    O'Neill, R. J.
    Doherty, J.
    Reynolds, G. P.
    SCHIZOPHRENIA BULLETIN, 2007, 33 (02) : 293 - 293
  • [17] Discovery and SAR of new benzazepines as potent and selective 5-HT2C receptor agonists for the treatment of obesity
    Smith, BM
    Smith, JM
    Tsai, JH
    Schultz, JA
    Gilson, CA
    Estrada, SA
    Chen, RR
    Park, DM
    Prieto, EB
    Gallardo, CS
    Sengupta, D
    Thomsen, WJ
    Saldana, HR
    Whelan, KT
    Menzaghi, F
    Webb, RR
    Beeley, NRA
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2005, 15 (05) : 1467 - 1470
  • [18] The 5-HT2C receptor, a target for panaceas
    Kennett, GA
    Bickerdike, MJ
    Vickers, SP
    Lightowler, SL
    Dourish, CT
    BRITISH JOURNAL OF PHARMACOLOGY, 2000, 131 : U47 - U47
  • [19] Functional Significance of Serotonin 5-HT2C Receptor Modulation of Gabaergic Neurons
    Oshibuchi, Hidehiro
    BIOLOGICAL PSYCHIATRY, 2014, 75 (09) : 68S - 68S
  • [20] A short history of the 5-HT2C receptor: from the choroid plexus to depression, obesity and addiction treatment
    Jose M. Palacios
    Angel Pazos
    Daniel Hoyer
    Psychopharmacology, 2017, 234 : 1395 - 1418