Two novel Tb (II) and Ca (II) Coordination Polymers: Crystal Structure and Inhibition of Human Cervical Cancer Cells

被引：0

作者：

Chen, Yan ^{[1
]}

Chen, Zhen-Dong ^{[2
]}

机构：

[1] Anhui Med Univ, Affilicated Hosp 2, Dept Gynaecol Obstet, Hefei, Anhui, Peoples R China

[2] Anhui Med Univ, Affilicated Hosp 2, Dept Med Oncol, Hefei, Anhui, Peoples R China

来源：

LATIN AMERICAN JOURNAL OF PHARMACY | 2018年 / 37卷 / 05期

关键词：

cervical cancer; metal-organic; X-ray diffraction; METAL-ORGANIC FRAMEWORK;

D O I：

暂无

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

In this study, two new metal-organic frameworks [Tb-2(NO3)(3)(TTTT)(NMP)(4)](NMP)(2) (1, NMP = N-methyl pyrrolidone) and (H2NMe2)[Ca-4(BTB)(3)](DMF)(2) (2, DMF = N, N-dimethylformamide) with diverse architectures have been successfully prepared via a one pot solvothermal synthesis by using the flexible tricarboxylic acid ligand 2,4,6-tris[(4-carboxyphenoxy) methyl]-1,3,5-trimethylbenzene (H3TTTT) and the rigid tricarboxylic acid ligand 4,4', 4 ''-benzene-1,3,5-tryil-tribenzoic acid (H3BTB). Both of the two complexes are characterized by single-crystal X-ray diffraction and elemental analysis. In addition, in vitro anticancer activity of compounds 1 and 2 on three human cervical cancer line cells (HeLa, SiHa and C33A) was further determined.

引用

页码：930 / 934

页数：5

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