Irradiation damage to frog inner ear during synchrotron radiation tomographic investigation

被引：5

作者：

Boistel, Renaud ^{[1
,2
,3
,4
]}

Pollet, Nicolas ^{[3
,5
,6
]}

Tinevez, Jean-Yves ^{[7
]}

Cloetens, Peter ^{[4
]}

Schlenker, Michel ^{[8
,9
]}

机构：

[1] CNRS, NAMC, Equipe Commun Acoust, UMR 8620, F-91405 Orsay, France

[2] Museum Natl Hist Nat, CNRS, Dept Ecol & Gest Biodiversite, UMR Mecanismes Adaptatifs Organismes Communautes, F-75231 Paris 5, France

[3] Univ Paris 11, F-91405 Orsay, France

[4] European Synchrotron Radiat Facil, F-38043 Grenoble, France

[5] CNRS, UMR 8080, F-91405 Orsay, France

[6] Univ Evry Val Essonne, Epigenom Project, F-91034 Evry, France

[7] Inst Curie Rech, CNRS, Lab Phys Chim Curie, UMR 168, F-75248 Paris 05, France

[8] CNRS, Inst Neel, F-38042 Grenoble, France

[9] Grenoble Inst Technol, F-38042 Grenoble, France

来源：

JOURNAL OF ELECTRON SPECTROSCOPY AND RELATED PHENOMENA | 2009年 / 170卷 / 1-3期

关键词：

X-ray; Inner ear; Radiation damage; Synchrotron radiation; Rana esculenta; Otoconia; Micro-tomography; QUANTITATIVE PHASE TOMOGRAPHY; OTOCONIA; PROTEIN;

D O I：

10.1016/j.elspec.2008.09.004

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

Unexpectedly severe radiation damage, showing up through deformation of the saccule, was encountered during a synchrotron radiation high-resolution (700 nm pixel size) tomographic observation of an inner ear, fixed in a formaldehyde solution, of the frog Rana esculenta. The visible displacement of the edge of the otoconia-filled part of the saccule amounted to about 100 mu m after an irradiation with 20.5 keV X-ray photons corresponding to a dose of 1.5 kGy for the protein matrix. The close-knit coexistence of organic and mineral components in the biological tissue may be linked to the dramatic increase of radiation dosage sensitivity. (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：37 / 41

页数：5

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