Does our limited knowledge of the mechanisms of neural stimulation limit its benefits for patients with overactive bladder? ICI-RS 2013

被引：5

作者：

Gajewski, Jerzy B. ^{[1
]}

Kanai, Anthony J. ^{[2
]}

Cardozo, Linda ^{[3
]}

Ikeda, Youko ^{[2
]}

Zabbarova, Irina V. ^{[4
]}

机构：

[1] Dalhousie Univ, Halifax, NS, Canada

[2] Univ Pittsburgh, Sch Med, Pittsburgh, PA USA

[3] Kings Coll Hosp London, London, England

[4] Univ Pittsburgh, Dept Med, Pittsburgh, PA USA

来源：

NEUROUROLOGY AND URODYNAMICS | 2014年 / 33卷 / 05期

关键词：

neural stimulation; overactive bladder; LOWER URINARY-TRACT; SACRAL NERVE-STIMULATION; NEUROMODULATION; INHIBITION; SYMPTOMS; CATS; RECEPTORS; BLIND;

D O I：

10.1002/nau.22610

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Introduction Neural stimulation has become an established minimally invasive treatment for various lower urinary tract symptoms. The results both short- and long-term are encouraging, however, there is still a lack of knowledge of obvious risk factors, which may affect the outcome of treatment. Although neural stimulation has been embraced by healthcare professionals and patients, the exact mechanism by which neural stimulation works is still unclear. Discussion A condense review of knowledge available on this topic is presented. Several research questions are raised. Outlines of research studies, both clinical and basic science, are suggested. Conclusions Further studies are necessary to understand mechanism of action of neural stimulation and its implications on treatment outcomes. Neurourol. Urodynam. 33:618-621, 2014. (c) 2014 Wiley Periodicals, Inc.

引用

页码：618 / 621

页数：4

共 30 条

[1] Long-Term Outcome and Surgical Interventions After Sacral Neuromodulation Implant for Lower Urinary Tract Symptoms: 14-Year Experience at 1 Center [J].