5,10-seco-neo-Clerodanes and neo-Clerodanes from Salvia microphylla

被引：39
作者：
Bautista, Elihu [1 ]
Toscano, Ruben A. [1 ]
Ortega, Alfredo [1 ]
机构：
[1] Univ Nacl Autonoma Mexico, Inst Quim, Mexico City 04510, DF, Mexico
来源：
JOURNAL OF NATURAL PRODUCTS | 2014年 / 77卷 / 04期
关键词：
UNPRECEDENTED SKELETON; ANTIPROTOZOAL ACTIVITY; SALVINORIN; DITERPENES;
D O I：
10.1021/np4009893
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Two new 5,10-seco-neo-clerodanes, salvimicrophyllins A and B (1 and 2), and two new neo-clerodanes, salvimicrophyllins C and D (3 and 4), were isolated from the leaves and flowers of Salvia microphylla. The structures of these compounds were elucidated mainly by analysis of their NMR spectroscopic and mass spectrometric data. The relative configurations of the salvimicrophyllins were determined by analysis of NOESY spectra and ECD curves, and the relative configuration of compound 2 was confirmed by single-crystal X-ray diffraction crystallography.
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收藏
页码：1088 / 1092
页数：5
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