IRAK4 degrader to take on innate immunity

被引：17
|
作者：
Mullard, Asher
机构：
来源：
NATURE BIOTECHNOLOGY | 2020年 / 38卷 / 11期
关键词：
D O I：
10.1038/s41587-020-0724-8
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Interest in anti-inflammatory IRAK4 signaling is ramping up, as small-molecule ‘degraders’ that bind both the kinase and E3 ubiquitin ligases prepare to take on traditional kinase inhibitors.
引用
收藏
页码：1221 / 1223
页数：3
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