Wide-range mass calibration for negative-ion DART mass spectrometry

被引：13
作者：
Gross, Juergen H. [1 ]
机构：
[1] Heidelberg Univ, Inst Organ Chem, D-69120 Heidelberg, Germany
来源：
EUROPEAN JOURNAL OF MASS SPECTROMETRY | 2014年 / 20卷 / 02期
关键词：
Direct analysis in real time; DART; mass spectrometry; Agilent ES tune mix; phosphazene; mass calibration; accurate mass; Fourier transform ion cyclotron resonance; FT-MS; Orbitrap; REAL-TIME; ELECTROSPRAY-IONIZATION; NONPOLAR COMPOUNDS; REFERENCE COMPOUND; OPEN-AIR; IDENTIFICATION; ULTRAMARK-1621; MS;
D O I：
10.1255/ejms.1266
中图分类号：
O64 [物理化学（理论化学）、化学物理学]; O56 [分子物理学、原子物理学];
学科分类号：
070203 ; 070304 ; 081704 ; 1406 ;
摘要：
A method for accurate mass calibration covering a wide m/z range in negative-ion direct analysis in real time mass spectrometry (DART-MS) is described. It is based on a commercially available tuning solution (Agilent ES tune mix) normally applied in electrospray ionization. This acetonitrile solution is composed of ammonium trifluoroacetate, betaine, 2,4,6-tris(heptafluoropropyl)-1,3,5-triazine, and various symmetrical hexakis-(fluoroalkoxy)-phosphazenes. Upon addition of 2% (v/v) trifluoroacetic acid in negative-ion DART-MS, this mixture yields negative ions covering a range of m/z 69 to m/z 2834. Validity of the calibration procedure is demonstrated on a Fourier transform ion cyclotron resonance mass spectrometer by application to polyethylene glycol diacid and [60]fullerene. Experimental conditions and a mass reference list are provided.
引用
收藏
页码：155 / 161
页数：7
相关论文
共 31 条
[1]   DART mass spectrometry and its applications in chemical analysis [J].
Chernetsova, E. S. ;
Morlock, G. E. ;
Revelsky, I. A. .
RUSSIAN CHEMICAL REVIEWS, 2011, 80 (03) :235-255
[2]   DART-Orbitrap MS: a novel mass spectrometric approach for the identification of phenolic compounds in propolis [J].
Chernetsova, Elena S. ;
Bromirski, Maciej ;
Scheibner, Olaf ;
Morlock, Gertrud E. .
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2012, 403 (10) :2859-2867
[3]   ID-CUBE direct analysis in real time high-resolution mass spectrometry and its capabilities in the identification of phenolic components from the green leaves of Bergenia crassifolia L. [J].
Chernetsova, Elena S. ;
Crawford, Elizabeth A. ;
Shikov, Alexander N. ;
Pozharitskaya, Olga N. ;
Makarov, Valery G. ;
Morlock, Gertrud E. .
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 2012, 26 (11) :1329-1337
[4]   DETERMINATION OF DRUGS AND DRUG-LIKE COMPOUNDS IN DIFFERENT SAMPLES WITH DIRECT ANALYSIS IN REAL TIME MASS SPECTROMETRY [J].
Chernetsova, Elena S. ;
Morlock, Gertrud E. .
MASS SPECTROMETRY REVIEWS, 2011, 30 (05) :875-883
[5]   Versatile new ion source for the analysis of materials in open air under ambient conditions [J].
Cody, RB ;
Laramée, JA ;
Durst, HD .
ANALYTICAL CHEMISTRY, 2005, 77 (08) :2297-2302
[6]   Soft Ionization of Saturated Hydrocarbons, Alcohols and Nonpolar Compounds by Negative-Ion Direct Analysis in Real-Time Mass Spectrometry [J].
Cody, Robert B. ;
Dane, A. John .
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2013, 24 (03) :329-334
[7]   Observation of Molecular Ions and Analysis of Nonpolar Compounds with the Direct Analysis in Real Time Ion Source [J].
Cody, Robert B. .
ANALYTICAL CHEMISTRY, 2009, 81 (03) :1101-1107
[8]   Evaluating a direct swabbing method for screening pesticides on fruit and vegetable surfaces using direct analysis in real time (DART) coupled to an Exactive benchtop orbitrap mass spectrometer [J].
Crawford, Elizabeth ;
Musselman, Brian .
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2012, 403 (10) :2807-2812
[9]   Rapid analysis of caffeine in various coffee samples employing direct analysis in real-time ionization-high-resolution mass spectrometry [J].
Danhelova, Hana ;
Hradecky, Jaromir ;
Prinosilova, Sarka ;
Cajka, Tomas ;
Riddellova, Katerina ;
Vaclavik, Lukas ;
Hajslova, Jana .
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2012, 403 (10) :2883-2889
[10]   Characterization of solid counterfeit drug samples by desorption electrospray ionization and direct-analysis-in-real-time coupled to time-of-flight mass spectrometry [J].
Fernandez, Facundo M. ;
Cody, Robert B. ;
Green, Michael D. ;
Hampton, Christina Y. ;
McGready, Rose ;
Sengaloundeth, Sivong ;
White, Nicholas J. ;
Newton, Paul N. .
CHEMMEDCHEM, 2006, 1 (07) :702-+
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