Prompt gamma neutron activation analysis of 10B and Gd in biological samples at the MEPhI reactor

被引：5

作者：

Khokhlov, V. F. ^{[1
]}

Zaitsev, K. N. ^{[2
]}

Beliayev, V. N. ^{[2
]}

Kulakov, V. N. ^{[1
]}

Lipengolts, A. A. ^{[1
,2
]}

Portnov, A. A. ^{[2
]}

机构：

[1] Fed Med Agcy, Burnasyan Fed Med Biophys Ctr, Moscow, Russia

[2] State Univ, Moscow Engn Phys Inst, Moscow, Russia

来源：

APPLIED RADIATION AND ISOTOPES | 2009年 / 67卷 / 7-8期

关键词：

BNCT; PGNAA; Research reactor; Monochromator; Boron; Gadolinium;

D O I：

10.1016/j.apradiso.2009.03.082

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The purpose of the work was to build a prompt gamma neutron activation analysis (PGNAA) facility at the MEPhI reactor for analyzing the content of various elements for NCT. The facility was implemented on a monochromatic neutron beam. Methods of quantitative B-10 and Gd measurement have been developed for pharmacokinetic studies. The facility is capable of measuring 1 mu g of B-10 and 10 mu g of Gd in biological samples with an error less than 10%. The detection limit of the facility is 0.3 mu g of B-10 and 2 mu g of Gd. Neutron flux attenuation within biological tissue samples was estimated and a new system for determining the elemental concentration was suggested. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：S251 / S253

页数：3

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