Macromolecular substrate recognition by prothrombinase is mediated by interactions at exosites in the enzyme complex.

被引：0

作者：

Krishnaswamy, S ^{[1
]}

Betz, A ^{[1
]}

机构：

[1] EMORY UNIV,DEPT MED,ATLANTA,GA 30322

来源：

BLOOD | 1996年 / 88卷 / 10期

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：2061 / 2061

页数：1

共 39 条

[1] Exosites determine macromolecular substrate recognition by prothrombinase
Krishnaswamy, S
Betz, A
BIOCHEMISTRY, 1997, 36 (40) : 12080 - 12086
[2] Exosite interactions control macromolecular substrate specificity of the prothrombinase complex
Betz, A
Krishnaswamy, S
THROMBOSIS AND HAEMOSTASIS, 1997, : P1751 - P1751
[3] Regions remote from the site of cleavage determine macromolecular substrate recognition by the prothrombinase complex
Betz, A
Krishnaswamy, S
JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (17) : 10709 - 10718
[4] DIFFERENTIATION OF ENZYME AND SUBSTRATE BINDING IN THE PROTHROMBINASE COMPLEX
TUCKER, MM
NESHEIM, ME
MANN, KG
BIOCHEMISTRY, 1983, 22 (19) : 4540 - 4546
[5] Extended interactions with prothrombinase enforce affinity and specificity for its macromolecular substrate
Orcutt, SJ
Pietropaolo, C
Krishnaswamy, S
JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (48) : 46191 - 46196
[6] Characterization of recombinant prethrombin 2 for the assessment of macromolecular substrate recognition by human prothrombinase.
Orcutt, S
Pietropaolo, C
Krishnaswamy, S
BLOOD, 1999, 94 (10) : 230A - 230A
[7] Exosite binding tethers the macromolecular substrate to the prothrombinase complex and directs cleavage at two spatially distinct sites
Boskovic, DS
Krishnaswamy, S
JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (49) : 38561 - 38570
[8] Selective inhibition of the prothrombinase complex: Factor Va alters macromolecular recognition of a tick anticoagulant peptide mutant by factor Xa
Betz, A
Vlasuk, GP
Bergum, PW
Krishnaswamy, S
BIOCHEMISTRY, 1997, 36 (01) : 181 - 191
[9] The recognition of meizothrombin-des fragment 1 by the prothrombinase complex is achieved through interactions at an exosite.
Baskovic, DS
Krishnaswamy, S
Poncz, M
BLOOD, 1999, 94 (10) : 230A - 230A
[10] A NEW SYSTEM FOR ANALYSIS OF ENZYME-KINETICS DATA APPLICABLE TO COMPLEX MACROMOLECULAR INTERACTIONS
LAMBERT, WC
PARRISH, DD
FENKART, D
KUO, HR
KOVACS, J
LAMBERT, MW
CLINICAL RESEARCH, 1993, 41 (02): : A441 - A441

← 1 2 3 4 →