The method of spheroid formation for 3D cultures of primary hepatocytes influences hepatocellular functions and hepatotoxicity

被引:0
|
作者
Moer, Jana [1 ]
Runge, Dieter [1 ]
Sanchez-Romero, Natalia [2 ]
Ullrich, Anett [1 ]
机构
[1] Primacyt Cell Culture Technol GmbH, Schwerin, Germany
[2] Cytes Biotechnol SL, R&D, Barcelona, Spain
关键词
D O I
暂无
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
THU324
引用
收藏
页码:S297 / S297
页数:1
相关论文
共 50 条
  • [1] The method of spheroid formation for 3D cultures of primary hepatocytes influences hepatocellular functions and hepatotoxicity
    Moer, J.
    Runge, D.
    Ullrich, A.
    TOXICOLOGY LETTERS, 2019, 314 : S185 - S185
  • [2] Comparison of 2D and 3D cultures of primary hepatocytes on hepatocellular functions and hepatotoxicity
    Dinter, H.
    Ullrich, A.
    Runge, D.
    TOXICOLOGY LETTERS, 2018, 295 : S121 - S121
  • [3] IN VITRO PRIMARY HUMAN HEPATOCYTE 3D SPHEROID MODEL FOR HEPATOTOXICITY STUDIES
    Li, Feng
    Parikh, Sweta
    Cao, Li
    Cooper, Kirsten
    Zuo, Rongjun
    DRUG METABOLISM AND PHARMACOKINETICS, 2019, 34 (01) : S36 - S36
  • [4] Development of a 3D spheroid system of primary human hepatocytes that supports efficient HBV infection
    Xu, S.
    Yang, H.
    Yu, M.
    Brocket, R.
    Xie, X.
    Gamelin, L.
    Chia, J.
    Lee, G.
    Mikaelian, I.
    Barry, V.
    Delaney, W.
    Cheng, G.
    Muench, R.
    JOURNAL OF VIRAL HEPATITIS, 2018, 25 : 191 - 191
  • [5] Considerations for 3D Spheroid Formation and Imaging
    Banks P.
    Sherman H.
    Genetic Engineering and Biotechnology News, 2019, 39 (09): : 56 - 58
  • [6] 3D Cultures: Effect on the Hepatocytes Functionality
    Miranda, Joana
    Carrondo, Manuel J. T.
    Alves, Paula M.
    CELLS AND CULTURE, 2010, 4 : 171 - 176
  • [7] A 3D spheroid model of quadruple cell co-culture with improved liver functions for hepatotoxicity prediction
    Sun, Baiyang
    Liang, Zihe
    Wang, Yupeng
    Yu, Yue
    Zhou, Xiaobing
    Geng, Xingchao
    Li, Bo
    TOXICOLOGY, 2024, 505
  • [8] Prediction of Drug-Induced Hepatotoxicity Using Long-Term Stable Primary Hepatic 3D Spheroid Cultures in Chemically Defined Conditions
    Vorrink, Sabine U.
    Zhou, Yitian
    Ingelman-Sundberg, Magnus
    Lauschke, Volker M.
    TOXICOLOGICAL SCIENCES, 2018, 163 (02) : 655 - 665
  • [9] Induction of hepatic transporters by dicloxacillin and flucloxacillin-Investigations in 3D spheroid primary human hepatocytes
    Jarvinen, Erkka
    Hammer, Helen S.
    Poetz, Oliver
    Stage, Tore B.
    BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2023, 132 : 3 - 4
  • [10] A chemotaxis-based explanation of spheroid formation in 3D cultures of breast cancer cells
    Bubba, Federica
    Pouchol, Camille
    Ferrand, Nathalie
    Vidal, Guillaume
    Almeida, Luis
    Perthame, Benoit
    Sabbah, Michele
    JOURNAL OF THEORETICAL BIOLOGY, 2019, 479 : 73 - 80