OSA: the new cardiovascular disease

被引:0
作者
Devulapally, Kiran [2 ]
Pongonis, Raymond, Jr. [3 ]
Khayat, Rami [1 ,2 ]
机构
[1] Ohio State Univ, OSU Sleep Heart Program, Columbus, OH 43210 USA
[2] Ohio State Univ, Div Pulm Crit Care & Sleep Med, Columbus, OH 43210 USA
[3] Northwestern Univ, Dept Med, Feinberg Sch Med, Feinberg Sch Med, Chicago, IL 60611 USA
关键词
OSA; Obstructive sleep apnea; Sleep apnea; Apnea; Apneic episodes; Sleep-disordered breathing; CHF; Congestive heart failure; HTN; Hypertension; Stroke; Pulmonary hypertension; CAD; Coronary artery disease; Arrhythmia; AHI; Blood pressure; OBSTRUCTIVE SLEEP-APNEA; POSITIVE AIRWAY PRESSURE; CORONARY-ARTERY-DISEASE; HEART-FAILURE PATIENTS; CHRONIC EPISODIC HYPOXIA; DAYTIME PULMONARY-HYPERTENSION; RIGHT-VENTRICULAR DYSFUNCTION; SYMPATHETIC-NERVE ACTIVITY; AMBULATORY BLOOD-PRESSURE; ENDOTHELIAL GROWTH-FACTOR;
D O I
10.1007/s10741-008-9101-2
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Obstructive sleep apnea (OSA), present in 5-15% of adults, is strongly associated with the incidence and poor outcome of hypertension, coronary artery disease, arrhythmia, heart failure, and stroke. Treatment of OSA completely reverses its cardiovascular consequences. In this review, we discuss the clinical evidence for the strong association between OSA and cardiovascular disease and present an argument for approaching OSA as a cardiovascular disease. We particularly focus on the causative relationship between OSA and hypertension, and on the increasingly recognized relationship between OSA and heart failure.
引用
收藏
页码:155 / 164
页数:10
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