OSA: the new cardiovascular disease

被引：0
作者：
Devulapally, Kiran [2 ]
Pongonis, Raymond, Jr. [3 ]
Khayat, Rami [1 ,2 ]
机构：
[1] Ohio State Univ, OSU Sleep Heart Program, Columbus, OH 43210 USA
[2] Ohio State Univ, Div Pulm Crit Care & Sleep Med, Columbus, OH 43210 USA
[3] Northwestern Univ, Dept Med, Feinberg Sch Med, Feinberg Sch Med, Chicago, IL 60611 USA
来源：
HEART FAILURE REVIEWS | 2009年 / 14卷 / 03期
关键词：
OSA; Obstructive sleep apnea; Sleep apnea; Apnea; Apneic episodes; Sleep-disordered breathing; CHF; Congestive heart failure; HTN; Hypertension; Stroke; Pulmonary hypertension; CAD; Coronary artery disease; Arrhythmia; AHI; Blood pressure; OBSTRUCTIVE SLEEP-APNEA; POSITIVE AIRWAY PRESSURE; CORONARY-ARTERY-DISEASE; HEART-FAILURE PATIENTS; CHRONIC EPISODIC HYPOXIA; DAYTIME PULMONARY-HYPERTENSION; RIGHT-VENTRICULAR DYSFUNCTION; SYMPATHETIC-NERVE ACTIVITY; AMBULATORY BLOOD-PRESSURE; ENDOTHELIAL GROWTH-FACTOR;
D O I：
10.1007/s10741-008-9101-2
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Obstructive sleep apnea (OSA), present in 5-15% of adults, is strongly associated with the incidence and poor outcome of hypertension, coronary artery disease, arrhythmia, heart failure, and stroke. Treatment of OSA completely reverses its cardiovascular consequences. In this review, we discuss the clinical evidence for the strong association between OSA and cardiovascular disease and present an argument for approaching OSA as a cardiovascular disease. We particularly focus on the causative relationship between OSA and hypertension, and on the increasingly recognized relationship between OSA and heart failure.
引用
收藏
页码：155 / 164
页数：10
相关论文
共 138 条
[1]  
Adhikary G, 2001, ADV EXP MED BIOL, V499, P297
[2]   Evidence for left ventricular dysfunction in patients with obstructive sleep apnoea syndrome [J].
Alchanatis, M ;
Tourkohoriti, G ;
Kosmas, EN ;
Panoutsopoulos, G ;
Kakouros, S ;
Papadima, K ;
Gaga, M ;
Jordanoglou, JB .
EUROPEAN RESPIRATORY JOURNAL, 2002, 20 (05) :1239-1245
[3]   Daytime pulmonary hypertension in patients with obstructive sleep apnea - The effect of continuous positive airway pressure on pulmonary hemodynamics [J].
Alchanatis, M ;
Tourkohoriti, G ;
Kakouros, S ;
Kosmas, E ;
Podaras, S ;
Jordanoglou, JB .
RESPIRATION, 2001, 68 (06) :566-572
[4]   Cardiac rhythm disturbances and ST-segment depression episodes in patients with obstructive sleep apnea-hypopnea syndrome and its mechanisms [J].
Alonso-Fernández, A ;
García-Río, F ;
Racionero, MA ;
Pino, JM ;
Ortuño, F ;
Martínez, I ;
Villamor, J .
CHEST, 2005, 127 (01) :15-22
[5]   Left ventricular hypertrophy and abnormal ventricular geometry in children and adolescents with obstructive sleep apnea [J].
Amin, RS ;
Kimball, TR ;
Bean, JA ;
Jeffries, JL ;
Willging, JP ;
Cotton, RT ;
Witt, SA ;
Glascock, BJ ;
Daniels, SR .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2002, 165 (10) :1395-1399
[6]   Daytime blood pressure elevation after nocturnal hypoxia [J].
Arabi, Y ;
Morgan, BJ ;
Goodman, B ;
Puleo, DS ;
Xie, AL ;
Skatrud, JB .
JOURNAL OF APPLIED PHYSIOLOGY, 1999, 87 (02) :689-698
[7]   Association of sleep-disordered breathing and the occurrence of stroke [J].
Arzt, M ;
Young, T ;
Finn, L ;
Skatrud, JB ;
Bradley, TD .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2005, 172 (11) :1447-1451
[8]   Pulmonary artery hypertension and sleep-disordered breathing - ACCP evidence-based clinical practice guidelines [J].
Atwood, CW ;
McCrory, D ;
Garcia, JGN ;
Abman, SH ;
Ahearn, GS .
CHEST, 2004, 126 (01) :72S-77S
[9]   Pulmonary arterial hypertension in patients with sleep apnoea syndrome [J].
Bady, E ;
Achkar, A ;
Pascal, S ;
Orvoen-Frija, E ;
Laaban, JP .
THORAX, 2000, 55 (11) :934-939
[10]   The severity of oxygen desaturation is predictive of carotid wall thickening and plaque occurrence [J].
Baguet, JP ;
Hammer, L ;
Lévy, P ;
Pierre, H ;
Launois, S ;
Mallion, JM ;
Pépin, JL .
CHEST, 2005, 128 (05) :3407-3412
12345678910