Ultra-sensitive immunoassay using VCSEL detection system

被引:23
|
作者
Mateus, CFR [1 ]
Huang, MCY
Chang-Hasnain, CJ
Foley, JE
Beatty, R
Li, P
Cunningham, BT
机构
[1] Univ Calif Berkeley, Dept Elect Engn & Comp Sci, Berkeley, CA 94720 USA
[2] Univ Calif Berkeley, Dept Bioengn, Berkeley, CA 94720 USA
[3] Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA
[4] SRU Biosyst, Woburn, MA 01801 USA
关键词
D O I
10.1049/el:20040491
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Highly sensitive protein characterisation on a new label-free biosensor system is reported. The system consists of a VCSEL, a plastic guided mode resonant filter and two pin detectors. It is suitable for measuring both static and dynamic interaction among proteins and can detect an antigen concentration as low as 1 pg/ml (6.7 femtoMolar).
引用
收藏
页码:649 / 651
页数:3
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