Ultra-sensitive immunoassay using VCSEL detection system

被引：24

作者：

Mateus, CFR ^{[1
]}

Huang, MCY

Chang-Hasnain, CJ

Foley, JE

Beatty, R

Li, P

Cunningham, BT

机构：

[1] Univ Calif Berkeley, Dept Elect Engn & Comp Sci, Berkeley, CA 94720 USA

[2] Univ Calif Berkeley, Dept Bioengn, Berkeley, CA 94720 USA

[3] Univ Calif Berkeley, Dept Mol & Cell Biol, Berkeley, CA 94720 USA

[4] SRU Biosyst, Woburn, MA 01801 USA

来源：

ELECTRONICS LETTERS | 2004年 / 40卷 / 11期

关键词：

D O I：

10.1049/el:20040491

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Highly sensitive protein characterisation on a new label-free biosensor system is reported. The system consists of a VCSEL, a plastic guided mode resonant filter and two pin detectors. It is suitable for measuring both static and dynamic interaction among proteins and can detect an antigen concentration as low as 1 pg/ml (6.7 femtoMolar).

引用

页码：649 / 651

页数：3

共 7 条

[1] Tunable VCSEL [J].

Chang-Hasnain, CJ .

IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS, 2000, 6 (06) :978-987

[2] A plastic colorimetric resonant optical biosensor for multiparallel detection of label-free biochemical interactions [J].

Cunningham, B ;

Lin, B ;

Qiu, J ;

Li, P ;

Pepper, J ;

Hugh, B .

SENSORS AND ACTUATORS B-CHEMICAL, 2002, 85 (03) :219-226

[3] Sub-ppb level detection of 2-hydroxybiphenyl using portable surface-plasmon-resonance immunosensor [J].

Gobi, KV ;

Kim, SJ ;

Harada, R ;

Miura, N .

ELECTROCHEMISTRY, 2003, 71 (06) :430-432

[4] Optical heterodyne surface-plasmon resonance biosensor [J].

Kuo, WC ;

Chou, C ;

Wu, HT .

OPTICS LETTERS, 2003, 28 (15) :1329-1331

[5]

MATEUS CFR, 2003, 2003 C LAS EL OPT CL

[6] Detection of Staphylococcus aureus enterotoxin B at femtomolar levels with a miniature integrated two-channel surface plasmon resonance (SPR) sensor [J].

Naimushin, AN ;

Soelberg, SD ;

Nguyen, DK ;

Dunlap, L ;

Bartholomew, D ;

Elkind, J ;

Melendez, J ;

Furlong, CE .

BIOSENSORS & BIOELECTRONICS, 2002, 17 (6-7) :573-584

[7] Proteomics to study genes and genomes [J].

Pandey, A ;

Mann, M .

NATURE, 2000, 405 (6788) :837-846

← 1 →