Circulating levels of adipose products and differences in fat distribution in the ovulatory and anovulatory phenotypes of polycystic ovary syndrome

被引:89
作者
Carmina, Enrico [2 ]
Bucchieri, Salvo [2 ]
Mansueto, Pasquale [2 ]
Rini, GiovamBattista [2 ]
Ferin, Michel
Lobo, Rogerio A. [1 ]
机构
[1] Columbia Univ, Med Ctr, Dept Obstet & Gynecol, New York, NY 10032 USA
[2] Univ Palermo, Dept Internal Med, Palermo, Italy
关键词
INSULIN-RESISTANCE; ANDROGEN EXCESS; DEHYDROEPIANDROSTERONE SULFATE; WOMEN; SERUM; ADIPONECTIN; SENSITIVITY; PREVALENCE; ULTRASOUND; PARAMETERS;
D O I
10.1016/j.fertnstert.2008.03.007
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Central fat distribution is increased in anovulatory women with polycystic ovary syndrome (PCOS) compared with ovulatory PCOS and matched controls. Among secreted adipocytokines, this is reflected mainly in lower levels of adiponectin. (Fertil Steril (R) 2009;91:1332-5. (C)2009 by American Society for Reproductive Medicine.)
引用
收藏
页码:1332 / 1335
页数:4
相关论文
共 28 条
[1]   Criteria for defining polycystic ovary syndrome as a predominantly hyperandrogenic syndrome: An Androgen Excess Society guideline [J].
Azziz, Ricardo ;
Carmina, Enrico ;
Dewailly, Didier ;
Diamanti-Kandarakis, Evanthia ;
Escobar-Morreale, Hector F. ;
Futterweit, Walter ;
Janssen, Onno E. ;
Legro, Richard S. ;
Norman, Robert J. ;
Taylor, Ann E. ;
Witchel, Selma F. .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2006, 91 (11) :4237-4245
[2]   Ultrasound assessment of the polycystic ovary: international consensus definitions [J].
Balen, AH ;
Laven, JSE ;
Tan, SL ;
Dewailly, D .
HUMAN REPRODUCTION UPDATE, 2003, 9 (06) :505-514
[3]   Metabolic characteristics of women with polycystic ovaries and oligo-amenorrhoea but normal androgen levels: implications for the management of polycystic ovary syndrome [J].
Barber, Thomas M. ;
Wass, John A. H. ;
McCarthy, Mark I. ;
Franks, Stephen .
CLINICAL ENDOCRINOLOGY, 2007, 66 (04) :513-517
[4]   Prevalence of idiopathic hirsutism [J].
Carmina, E .
EUROPEAN JOURNAL OF ENDOCRINOLOGY, 1998, 139 (04) :421-423
[5]   Endothelial dysfunction in PCOS: Role of obesity and adipose hormones [J].
Carmina, E ;
Orio, F ;
Palomba, S ;
Longo, RA ;
Cascella, T ;
Colao, A ;
Lombardi, G ;
Rini, GB ;
Lobo, RA .
AMERICAN JOURNAL OF MEDICINE, 2006, 119 (04) :356.e1-356.e6
[6]  
Carmina E, 1997, HUM REPROD, V12, P905
[7]   Phenotypic variation in hyperandrogenic women influences the findings of abnormal metabolic and cardiovascular risk parameters [J].
Carmina, E ;
Chu, MC ;
Longo, RA ;
Rini, GB ;
Lobo, RA .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2005, 90 (05) :2545-2549
[8]   Evidence for altered adipocyte function in polycystic ovary syndrome [J].
Carmina, E ;
Orio, F ;
Palomba, S ;
Cascella, T ;
Longo, RA ;
Colao, AM ;
Lombardi, G ;
Lobo, RA .
EUROPEAN JOURNAL OF ENDOCRINOLOGY, 2005, 152 (03) :389-394
[9]   Ovarian size and blood flow in women with polycystic ovary syndrome and their correlations with endocrine parameters [J].
Carmina, E ;
Orio, F ;
Palomba, S ;
Longo, RA ;
Lombardi, G ;
Lobo, RA .
FERTILITY AND STERILITY, 2005, 84 (02) :413-419
[10]   Use of fasting blood to assess the prevalence of insulin resistance in women with polycystic ovary syndrome [J].
Carmina, E ;
Lobo, RA .
FERTILITY AND STERILITY, 2004, 82 (03) :661-665