Underuse of epinephrine for the treatment of anaphylaxis: missed opportunities

被引:89
作者
Prince, Benjamin T. [1 ]
Mikhail, Irene [1 ]
Stukus, David R. [1 ]
机构
[1] Ohio State Univ, Coll Med, Nationwide Childrens Hosp, Div Allergy & Immunol, Columbus, OH 43210 USA
关键词
anaphylaxis; epinephrine; emergency department; food allergy; FOOD-ALLERGIC REACTIONS; EMERGENCY-DEPARTMENT; AUTO-INJECTORS; FOLLOW-UP; MANAGEMENT; CHILDREN; DIAGNOSIS; ADRENALINE; EPIPEN; AUTOINJECTORS;
D O I
10.2147/JAA.S159400
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Epinephrine is the only effective treatment for anaphylaxis but studies routinely show underutilization. This is especially troubling given the fact that fatal anaphylaxis has been associated with delayed administration of epinephrine. Many potential barriers exist to the proper use of epinephrine during an anaphylactic reaction. This article will explore both patient- and physician-related factors, as well as misconceptions that all contribute to the underuse of epinephrine for the treatment of anaphylaxis.
引用
收藏
页码:143 / 151
页数:9
相关论文
共 59 条
[1]   Do Corticosteroids Prevent Biphasic Anaphylaxis? [J].
Alqurashi, Waleed ;
Ellis, Anne K. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2017, 5 (05) :1194-1206
[2]  
Alvarez-Perea A, 2015, J INVEST ALLERG CLIN, V25, P288
[4]   Factors determining the ability of parents to effectively administer intramuscular adrenaline to food allergic children [J].
Arkwright, PD ;
Farragher, AJ .
PEDIATRIC ALLERGY AND IMMUNOLOGY, 2006, 17 (03) :227-229
[5]   Retrospective Study of Drug-induced Anaphylaxis Treated in the Emergency Department or Hospital: Patient Characteristics, Management, and 1-Year Follow-up [J].
Banerji, Aleena ;
Rudders, Susan ;
Clark, Sunday ;
Wei, Wenhui ;
Long, Aidan A. ;
Camargo, Carlos A., Jr. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2014, 2 (01) :46-51
[6]   Misuse of medical devices: a persistent problem in self-management of asthma and allergic disease [J].
Bonds, Rana S. ;
Asawa, Ashish ;
Ghazi, Aasia I. .
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2015, 114 (01) :74-U104
[7]   Diagnosis and treatment of food allergic reactions in pediatric emergency settings [J].
Brooks, Christopher ;
Coffman, Alexa ;
Erwin, Elizabeth ;
Mikhail, Irene .
ANNALS OF ALLERGY ASTHMA & IMMUNOLOGY, 2017, 119 (05) :467-468
[8]   What Physical Examination Findings and Diagnostic Imaging Modalities Are Most Useful in the Diagnosis of Scaphoid Fractures? [J].
Brown, Michael ;
Jones, Alan ;
Newman, David .
ANNALS OF EMERGENCY MEDICINE, 2015, 65 (03) :308-309
[9]   Outcomes of Allergy/Immunology Follow-Up After an Emergency Department Evaluation for Anaphylaxis [J].
Campbell, Ronna L. ;
Park, Miguel A. ;
Kueber, Michael A., Jr. ;
Lee, Sangil ;
Hagan, John B. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2015, 3 (01) :88-93
[10]   Epinephrine in Anaphylaxis: Higher Risk of Cardiovascular Complications and Overdose After Administration of Intravenous Bolus Epinephrine Compared with Intramuscular Epinephrine [J].
Campbell, Ronna L. ;
Bellolio, Fernanda ;
Knutson, Benjamin D. ;
Bellamkonda, Venkatesh R. ;
Fedko, Martin G. ;
Nestler, David M. ;
Hess, Erik P. .
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, 2015, 3 (01) :76-80