Cell Interactions with Biomaterials Gradients and Arrays

被引：21

作者：

Simon, Carl G. ^{[1
]}

Yang, Yanyin ^{[1
]}

Thomas, Vinoy ^{[2
]}

Dorsey, Shauna M. ^{[1
]}

Morgan, Abby W. ^{[1
]}

机构：

[1] Natl Inst Stand & Technol, Div Polymers, Gaithersburg, MD 20899 USA

[2] Natl Inst Stand & Technol, Div Ceram, Gaithersburg, MD 20899 USA

来源：

COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING | 2009年 / 12卷 / 06期

关键词：

Biomaterials; cell adhesion; cell-material interactions; combinatorial screening; gradient; hydrogel; microarray; polymer; tissue engineering; IMMOBILIZED CONCENTRATION GRADIENTS; GUIDE NEURITE OUTGROWTH; PLATELET-ADHESION; COMBINATORIAL LIBRARIES; OSTEOBLAST RESPONSE; ZONAL ORGANIZATION; MORPHOGEN GRADIENT; SURFACE-CHEMISTRY; AXON GUIDANCE; GROWTH;

D O I：

10.2174/138620709788681961

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Gradients and arrays have become very useful to the fields of tissue engineering and biomaterials. Both gradients and arrays make efficient platforms for screening cell response to biomaterials. Graded biomaterials also have functional applications and make useful substrates for fundamental studies of cell phenomena such as migration. This article will review the use of gradients and arrays in tissue engineering and biomaterials research, with a focus on cellular and biologic responses.

引用

页码：544 / 553

页数：10

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