Alexithymia and neuroendocrine-immune response in patients with autoimmune diseases -: Preliminary results on relationship between alexithymic construct and TNF-α levels

被引:25
作者
Bruni, R.
Serino, F. M.
Galluzzo, S.
Coppolino, G.
Cacciapaglia, E.
Vadacca, M.
Nilo, S.
Terminio, N.
Afeltra, A.
机构
[1] Dept Psychiat, Rome, Italy
[2] Dept Immunol & Clin Med, Rome, Italy
[3] Dept Geriatr, Rome, Italy
来源
BASIC AND CLINICAL ASPECTS OF NEUROENDOCRINE IMMUNOLOGY IN RHEUMATIC DISEASES | 2006年 / 1069卷
关键词
alexithymia; rheumatoid arthritis; neuroendocrine immune system; TNF-alpha;
D O I
10.1196/annals.1351.018
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Alexithymia is conceptualized as a disorder of emotion regulation mechanisms, which involves a dissociation of emotional and physic responses to life events and bodily sensations. Our results might suggest a possible relationship between the alexithymic construct and TNF levels in RA patients. These preliminary findings corroborate the integrated bidirectional interactions between neuropsychological mechanisms and the neuroendocrine-immune system in patients affected by autoimmune diseases and contribute to finding a common biological pathway linking alexithymia and autoimmune-inflammatory diseases.
引用
收藏
页码:208 / 211
页数:4
相关论文
共 7 条
  • [1] PSYCHONEUROIMMUNOLOGY - INTERACTIONS BETWEEN THE NERVOUS-SYSTEM AND THE IMMUNE-SYSTEM
    ADER, R
    COHEN, N
    FELTEN, D
    [J]. LANCET, 1995, 345 (8942) : 99 - 103
  • [2] Developments in glucocorticoid therapy
    Bijlsma, JWJ
    Saag, KG
    Buttgereit, F
    da Silva, JAP
    [J]. RHEUMATIC DISEASE CLINICS OF NORTH AMERICA, 2005, 31 (01) : 1 - +
  • [3] Cross validation of the factor structure of the 20-item Toronto alexithymia scale: An Italian multicenter study
    Bressi, C
    Taylor, G
    Parker, J
    Bressi, S
    Brambilla, V
    Aguglia, E
    Allegranti, I
    Bongiorno, A
    Giberti, F
    Bucca, M
    Todarello, O
    Callegari, C
    Vender, S
    Gala, C
    Invernizzi, G
    [J]. JOURNAL OF PSYCHOSOMATIC RESEARCH, 1996, 41 (06) : 551 - 559
  • [4] Cutolo M, 1999, CLIN EXP RHEUMATOL, V17, P515
  • [5] Is there a psychoneuroimmunological pathway between alexithymia and immunity? Immune and physiological correlates of alexithymia
    Guilbaud, O
    Corcos, M
    Hjalmarsson, L
    Loas, G
    Jeammet, P
    [J]. BIOMEDICINE & PHARMACOTHERAPY, 2003, 57 (07) : 292 - 295
  • [6] PREVALENCE OF ALEXITHYMIC CHARACTERISTICS IN PSYCHOSOMATIC PATIENTS
    SIFNEOS, PE
    [J]. PSYCHOTHERAPY AND PSYCHOSOMATICS, 1973, 22 (2-6) : 255 - 262
  • [7] Taylor G.J., 2000, HDB EMOTIONAL INTELL, P301