Flash Visual Evoked Potentials in Normal Pomeranian Dogs and Those with Canine Cognitive Dysfunction

被引：0

作者：

Hamnilrat, Thanawut ^{[1
,2
]}

Lekcharoensuk, Chalermpol ^{[4
]}

Choochaermporn, Piyathip ^{[3
]}

Thayananuphat, Aree ^{[4
]}

机构：

[1] Kasetsart Univ, Ctr Agr Biotechnol, Nakhon Pathom 73140, Thailand

[2] Ctr Excellence Agr Biotechnol AG BIO PERDO CHE, Nakhon Pathom 73140, Thailand

[3] Kasetsart Univ, Fac Vet Med, Kasetsart Vet Teaching Hosp, Bangkok 10900, Thailand

[4] Kasetsart Univ, Fac Vet Med, Dept Compan Anim Clin Sci, Nakhon Pathom 73140, Thailand

来源：

THAI JOURNAL OF VETERINARY MEDICINE | 2015年 / 45卷 / 03期

关键词：

brain atrophy; cognitive dysfunction; dog; Pomeranian; visual evoked potential; ALZHEIMERS-DISEASE; BRAIN; MODEL;

D O I：

暂无

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Visual evoked potential (VEP) is a useful technique for evaluation of optic nerve pathway and diagnosis of human Alzheimer's disease. Canine cognitive dysfunction (CCD) is an age-related neurobehavioural syndrome which is commonly underdiagnosed in dogs. In the present study, VEPs were recorded from 28 Pomeranian dogs including 9 normal dogs aged between 1-8 years, 9 normal dogs aged over 8 years, and 10 dogs with signs of CCD. Brain atrophy in 8 CCD dogs was confirmed by CT scan. The other two dogs with signs of CCD had tumor which was confirmed by CT scan and cerebrospinal fluid. The VEP components of dogs over and under 8 years old were not statistically different (p>0.05). P2 and P3 of the dogs with CCD were longer than those of the normal dogs (p<0.05). The VEPs in dogs with CCD and tumor had different patterns. In conclusion, VEP is a promising tool for the diagnosis of CCD in aging dogs.

引用

页码：323 / 329

页数：7

共 22 条

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Spadavecchia, Luciano
Maculotti, Marco
Bandini, Fabio
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