Reactions of 1,2-& 1,4-dihydropyridines

被引:15
作者
Singh, Sunil K. [1 ]
Sharma, Vivek K. [2 ]
机构
[1] Univ Delhi, Kirori Mal Coll, Dept Chem, Delhi 110007, India
[2] Univ Delhi, Dept Chem, Delhi 110007, India
关键词
1,2-1,4-Dihydropyridines; aromatization; cycloaddition; diamination; oxidation; oxyselenation; photodimerisation; rearrangement; DIELS-ALDER REACTION; ORGANOCATALYTIC TRANSFER HYDROGENATION; ASYMMETRIC TRANSFER HYDROGENATION; ROOM-TEMPERATURE AROMATIZATION; CONVENIENT OXIDIZING-AGENT; HIGH-YIELD OXIDATION; ONE-POT SYNTHESIS; HANTZSCH 1,4-DIHYDROPYRIDINES; EFFICIENT OXIDATION; ORGANIC AZIDES;
D O I
10.2174/1385272819666140201003050
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
This review provides a comprehensive compilation of available literature concerning the reactions of 1,2- & 1,4-dihydropyridines, which have opened new frontiers in the area of synthetic and medicinal chemistry. These reactions mainly include cycloaddition, 1,3-Dipolar cycloaddition, alkoxy halogenation, diamination, hydroxyamination, oxidation, hydroxylation, photooxygenation reaction, nucleophilic addition, cyclization, electrophilic substitution, multicomponent reactions (MCRs) and rearrangement reactions. 1,4-Dihydropyridine has also been used in hydrogen transfer reactions as a synthetic NADH model for the reduction of several important molecules in excellent yields.
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页码:1159 / 1207
页数:49
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