Tunable Structures and Properties of Electrospun Regenerated Silk Fibroin Mats Annealed in Water Vapor at Different Times and Temperatures

被引：26

作者：

Huang, Xiangyu ^{[1
]}

Fan, Suna ^{[1
]}

Altayp, Alhadi Ibrahim Mohammed ^{[1
]}

Zhang, Yaopeng ^{[1
]}

Shao, Huili ^{[1
]}

Hu, Xuechao ^{[1
]}

Xie, Minkai ^{[2
]}

Xu, Yuemin ^{[2
]}

机构：

[1] Donghua Univ, Coll Mat Sci & Engn, State Key Lab Modificat Chem Fibers & Polymer Mat, Shanghai 201620, Peoples R China

[2] Shanghai Jiao Tong Univ, Peoples Hosp 6, Dept Urol, Shanghai 200233, Peoples R China

来源：

JOURNAL OF NANOMATERIALS | 2014年 / 2014卷

基金：

中国国家自然科学基金;

关键词：

SOLID-STATE; FIBERS; NANOFIBERS; SCAFFOLDS; MODEL; BIOMATERIALS; CONFORMATION; NMR;

D O I：

10.1155/2014/682563

中图分类号：

TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Regenerated silk fibroin (SF) mats were fabricated using electrospinning technique, followed by mild water vapor annealing to effectively tune the structures and improve the mechanical properties of the mats at different annealing times and temperatures. The breaking strength and the breaking energy of the mats treated with water vapor at 65 degrees C for 12 h reached 6.0MPa and 171.7 J/kg, respectively. The conformational transition of the SF mats was significantly influenced by the treating temperature, while the influence of time was comparatively limited. The influence is consistent with the time-temperature equivalent principle and would be helpful for the preparation of water-vapor-annealed silk-based biomaterials for various applications.

引用

页数：7

共 35 条

[1] CONFORMATION CHARACTERIZATION OF BOMBYX-MORI SILK FIBROIN IN THE SOLID-STATE BY HIGH-FREQUENCY C-13 CROSS POLARIZATION MAGIC ANGLE SPINNING NMR, X-RAY-DIFFRACTION, AND INFRARED-SPECTROSCOPY [J].

ASAKURA, T ;

KUZUHARA, A ;

TABETA, R ;

SAITO, H .

MACROMOLECULES, 1985, 18 (10) :1841-1845

[2] Determination of the torsion angles of alanine and glycine residues of model compounds of spider silk (AGG)10 using solid-state NMR methods [J].

Ashida, J ;

Ohgo, K ;

Komatsu, K ;

Kubota, A ;

Asakura, T .

JOURNAL OF BIOMOLECULAR NMR, 2003, 25 (02) :91-103

[3] Thermally induced α-helix to β-sheet transition in regenerated silk fibers and films [J].

Drummy, LF ;

Phillips, DM ;

Stone, MO ;

Farmer, BL ;

Naik, RR .

BIOMACROMOLECULES, 2005, 6 (06) :3328-3333

[4] Regenerated Silk Fibroin Nanofibrous Matrices Treated with 75% Ethanol Vapor for Tissue-Engineering Applications [J].

Fan, Linpeng ;

Wang, Hongsheng ;

Zhang, Kuihua ;

He, Chuanglong ;

Cai, Zengxiao ;

Mo, Xiumei .

JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, 2012, 23 (1-4) :497-508

[5] Electrospun regenerated silk fibroin mats with enhanced mechanical properties [J].

Fan, Suna ;

Zhang, Yaopeng ;

Shao, Huili ;

Hu, Xuechao .

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, 2013, 56 :83-88

[6]

Fraser R., 2012, Conformation in fibrous proteins and related synthetic polypeptides

[7] RAMAN SPECTROSCOPIC STUDY OF POLY(BETA-BENZYL-L-ASPARTATE) AND SEQUENTIAL POLYPEPTIDES [J].

FRUSHOUR, BG ;

KOENIG, JL .

BIOPOLYMERS, 1975, 14 (10) :2115-2135

[8] Dissolution of Bombyx mori silk fibroin in the calcium nitrate tetrahydrate-methanol system and aspects of wet spinning of fibroin solution [J].

Ha, SW ;

Park, YH ;

Hudson, SM .

BIOMACROMOLECULES, 2003, 4 (03) :488-496

[9] Preparation and characterization of electrospun silk fibroin/sericin blend fibers [J].

Hang, Yichun ;

Zhang, Yaopeng ;

Jin, Yuan ;

Shao, Huili ;

Hu, Xuechao .

JOURNAL OF MATERIALS RESEARCH, 2011, 26 (23) :2931-2937

[10] Dynamic protein-water relationships during β-sheet formation [J].

Hu, Xiao ;

Kaplan, David ;

Cebe, Peggy .

MACROMOLECULES, 2008, 41 (11) :3939-3948

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