Rabbit Models for Studying Human Infectious Diseases

被引：3
作者：
Peng, Xuwen [1 ]
Knouse, John A. [1 ]
Hernon, Krista M. [1 ]
机构：
[1] Penn State Univ, Coll Med, Dept Comparat Med, Hershey, PA USA
来源：
COMPARATIVE MEDICINE | 2015年 / 65卷 / 06期
关键词：
HERPES-SIMPLEX-VIRUS; CELL LEUKEMIA-VIRUS; TREPONEMA-PARALUIS-CUNICULI; T-CELL; TRANSGENIC RABBIT; HUMAN-PAPILLOMAVIRUS; CONGENITAL-SYPHILIS; HIV-1; INFECTION; ANIMAL-MODELS; HTLV-I;
D O I：
暂无
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
Using an appropriate animal model is crucial for mimicking human disease conditions, and various facets including genetics, anatomy, and pathophysiology should be considered before selecting a model. Rabbits (Oryctolagus cuniculus) are well known for their wide use in production of antibodies, eye research, atherosclerosis and other cardiovascular diseases. However, a systematic description of the rabbit as primary experimental models for the study of various human infectious diseases is unavailable. This review focuses on the human infectious diseases for which rabbits are considered a classic or highly appropriate model, including AIDS (caused by HIV1), adult T-cell leukemia-lymphoma (human T-lymphotropic virus type 1), papilloma or carcinoma (human papillomavirus), herpetic stromal keratitis (herpes simplex virus type 1), tuberculosis (Mycobacterium tuberculosis), and syphilis (Treponema pallidum). In addition, particular aspects of the husbandry and care of rabbits used in studies of human infectious diseases are described.
引用
收藏
页码：499 / 507
页数：9
相关论文
共 144 条
[71]  
Kreider J W, 1985, Clin Dermatol, V3, P20, DOI 10.1016/0738-081X(85)90046-X
[72]   HIGH-EFFICIENCY INDUCTION OF PAPILLOMAS IN-VIVO USING RECOMBINANT COTTONTAIL RABBIT PAPILLOMAVIRUS DNA [J].
KREIDER, JW ;
CLADEL, NM ;
PATRICK, SD ;
WELSH, PA ;
DIANGELO, SL ;
BOWER, JM ;
CHRISTENSEN, ND .
JOURNAL OF VIROLOGICAL METHODS, 1995, 55 (02) :233-244
[73]   INFECTION OF RABBITS WITH HUMAN IMMUNODEFICIENCY VIRUS-1 - A SMALL ANIMAL-MODEL FOR ACQUIRED IMMUNODEFICIENCY SYNDROME [J].
KULAGA, H ;
FOLKS, T ;
RUTLEDGE, R ;
TRUCKENMILLER, ME ;
GUGEL, E ;
KINDT, TJ .
JOURNAL OF EXPERIMENTAL MEDICINE, 1989, 169 (01) :321-326
[74]   INFECTION OF RABBIT T-CELL AND MACROPHAGE LINES WITH HUMAN IMMUNODEFICIENCY VIRUS [J].
KULAGA, H ;
FOLKS, TM ;
RUTLEDGE, R ;
KINDT, TJ .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (12) :4455-4459
[75]  
KWON BS, 1981, INVEST OPHTH VIS SCI, V21, P442
[76]   Biological basis for syphilis [J].
LaFond, RE ;
Lukehart, SA .
CLINICAL MICROBIOLOGY REVIEWS, 2006, 19 (01) :29-+
[77]  
LAIBSON PR, 1966, ARCH OPHTHALMOL-CHIC, V75, P254
[78]   Tuberculosis unleashed:: the impact of human immunodeficiency virus infection on the host granulomatous response to Mycobacterium tuberculosis [J].
Lawn, SD ;
Butera, ST ;
Shinnick, TM .
MICROBES AND INFECTION, 2002, 4 (06) :635-646
[79]   Tuberculosis [J].
Lawn, Stephen D. ;
Zumla, Alimuddin I. .
LANCET, 2011, 378 (9785) :57-72
[80]   HIV-1 MEDIATES RAPID APOPTOSIS OF LYMPHOCYTES FROM HUMAN CD4 TRANSGENIC BUT NOT NORMAL RABBITS [J].
LENO, W ;
HAGUE, BF ;
TELLER, R ;
KINDT, TJ .
VIROLOGY, 1995, 213 (02) :450-454
3456789101112